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Deep Sequencing of Varicella-Zoster Virus in Aqueous Humor From a Patient With Acute Retinal Necrosis Presenting With Acute Glaucoma

We report a case of acute retinal necrosis presenting with acute glaucoma preceding inflammatory signs by several days. High-throughput sequencing on aqueous humor revealed a low-level diversity in the viral genome comparable to diversity seen in cutaneous vesicles in contrast to high diversity in e...

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Autores principales: von Hofsten, Joanna, Ringlander, Johan, Norberg, Peter, Zetterberg, Madeleine, Andersson, Maria, Lindh, Magnus, Bergström, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305702/
https://www.ncbi.nlm.nih.gov/pubmed/32587876
http://dx.doi.org/10.1093/ofid/ofaa198
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author von Hofsten, Joanna
Ringlander, Johan
Norberg, Peter
Zetterberg, Madeleine
Andersson, Maria
Lindh, Magnus
Bergström, Tomas
author_facet von Hofsten, Joanna
Ringlander, Johan
Norberg, Peter
Zetterberg, Madeleine
Andersson, Maria
Lindh, Magnus
Bergström, Tomas
author_sort von Hofsten, Joanna
collection PubMed
description We report a case of acute retinal necrosis presenting with acute glaucoma preceding inflammatory signs by several days. High-throughput sequencing on aqueous humor revealed a low-level diversity in the viral genome comparable to diversity seen in cutaneous vesicles in contrast to high diversity in encephalitis.
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spelling pubmed-73057022020-06-24 Deep Sequencing of Varicella-Zoster Virus in Aqueous Humor From a Patient With Acute Retinal Necrosis Presenting With Acute Glaucoma von Hofsten, Joanna Ringlander, Johan Norberg, Peter Zetterberg, Madeleine Andersson, Maria Lindh, Magnus Bergström, Tomas Open Forum Infect Dis Brief Report We report a case of acute retinal necrosis presenting with acute glaucoma preceding inflammatory signs by several days. High-throughput sequencing on aqueous humor revealed a low-level diversity in the viral genome comparable to diversity seen in cutaneous vesicles in contrast to high diversity in encephalitis. Oxford University Press 2020-05-26 /pmc/articles/PMC7305702/ /pubmed/32587876 http://dx.doi.org/10.1093/ofid/ofaa198 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
von Hofsten, Joanna
Ringlander, Johan
Norberg, Peter
Zetterberg, Madeleine
Andersson, Maria
Lindh, Magnus
Bergström, Tomas
Deep Sequencing of Varicella-Zoster Virus in Aqueous Humor From a Patient With Acute Retinal Necrosis Presenting With Acute Glaucoma
title Deep Sequencing of Varicella-Zoster Virus in Aqueous Humor From a Patient With Acute Retinal Necrosis Presenting With Acute Glaucoma
title_full Deep Sequencing of Varicella-Zoster Virus in Aqueous Humor From a Patient With Acute Retinal Necrosis Presenting With Acute Glaucoma
title_fullStr Deep Sequencing of Varicella-Zoster Virus in Aqueous Humor From a Patient With Acute Retinal Necrosis Presenting With Acute Glaucoma
title_full_unstemmed Deep Sequencing of Varicella-Zoster Virus in Aqueous Humor From a Patient With Acute Retinal Necrosis Presenting With Acute Glaucoma
title_short Deep Sequencing of Varicella-Zoster Virus in Aqueous Humor From a Patient With Acute Retinal Necrosis Presenting With Acute Glaucoma
title_sort deep sequencing of varicella-zoster virus in aqueous humor from a patient with acute retinal necrosis presenting with acute glaucoma
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305702/
https://www.ncbi.nlm.nih.gov/pubmed/32587876
http://dx.doi.org/10.1093/ofid/ofaa198
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