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Formulation of anti-acne concealer containing cinnamon oil with antimicrobial activity against Propionibacterium acnes
This study aimed to develop an anti-acne concealer containing essential oil with anti-Propionibacterium acnes activity. Antimicrobial activity of cinnamon oil, galangal oil, and eucalyptus oil against P. acnes DMST 14916 was assayed using agar disc diffusion and the broth dilution method. Cinnamon o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305778/ https://www.ncbi.nlm.nih.gov/pubmed/32587816 http://dx.doi.org/10.4103/japtr.JAPTR_1_20 |
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author | Veerasophon, Jinmica Sripalakit, Pattana Saraphanchotiwitthaya, Aurasorn |
author_facet | Veerasophon, Jinmica Sripalakit, Pattana Saraphanchotiwitthaya, Aurasorn |
author_sort | Veerasophon, Jinmica |
collection | PubMed |
description | This study aimed to develop an anti-acne concealer containing essential oil with anti-Propionibacterium acnes activity. Antimicrobial activity of cinnamon oil, galangal oil, and eucalyptus oil against P. acnes DMST 14916 was assayed using agar disc diffusion and the broth dilution method. Cinnamon oil showed the maximum inhibitory activity against P. acnes with a clear zone diameter of 36.75 ± 1.06 mm, compared to 14.67 ± 0.58 and 41.83 ± 1.04 mm for tea tree oil and clindamycin, respectively. The minimum inhibitory concentration value of cinnamon oil was 5 mg/mL. Among five formulations of concealer incorporating 0.5% w/w cinnamon oil, F4 provided good texture, coverage, and spreadability with anti-P. acnes activity and stable under determined storage conditions. Cinnamon oil could be a promising cosmetic ingredient for anti-acne products, and F4 concealer may be useful for both covering skin imperfections and the management of acne. |
format | Online Article Text |
id | pubmed-7305778 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-73057782020-06-24 Formulation of anti-acne concealer containing cinnamon oil with antimicrobial activity against Propionibacterium acnes Veerasophon, Jinmica Sripalakit, Pattana Saraphanchotiwitthaya, Aurasorn J Adv Pharm Technol Res Original Article This study aimed to develop an anti-acne concealer containing essential oil with anti-Propionibacterium acnes activity. Antimicrobial activity of cinnamon oil, galangal oil, and eucalyptus oil against P. acnes DMST 14916 was assayed using agar disc diffusion and the broth dilution method. Cinnamon oil showed the maximum inhibitory activity against P. acnes with a clear zone diameter of 36.75 ± 1.06 mm, compared to 14.67 ± 0.58 and 41.83 ± 1.04 mm for tea tree oil and clindamycin, respectively. The minimum inhibitory concentration value of cinnamon oil was 5 mg/mL. Among five formulations of concealer incorporating 0.5% w/w cinnamon oil, F4 provided good texture, coverage, and spreadability with anti-P. acnes activity and stable under determined storage conditions. Cinnamon oil could be a promising cosmetic ingredient for anti-acne products, and F4 concealer may be useful for both covering skin imperfections and the management of acne. Wolters Kluwer - Medknow 2020 2020-04-22 /pmc/articles/PMC7305778/ /pubmed/32587816 http://dx.doi.org/10.4103/japtr.JAPTR_1_20 Text en Copyright: © 2020 Journal of Advanced Pharmaceutical Technology & Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Veerasophon, Jinmica Sripalakit, Pattana Saraphanchotiwitthaya, Aurasorn Formulation of anti-acne concealer containing cinnamon oil with antimicrobial activity against Propionibacterium acnes |
title | Formulation of anti-acne concealer containing cinnamon oil with antimicrobial activity against Propionibacterium acnes |
title_full | Formulation of anti-acne concealer containing cinnamon oil with antimicrobial activity against Propionibacterium acnes |
title_fullStr | Formulation of anti-acne concealer containing cinnamon oil with antimicrobial activity against Propionibacterium acnes |
title_full_unstemmed | Formulation of anti-acne concealer containing cinnamon oil with antimicrobial activity against Propionibacterium acnes |
title_short | Formulation of anti-acne concealer containing cinnamon oil with antimicrobial activity against Propionibacterium acnes |
title_sort | formulation of anti-acne concealer containing cinnamon oil with antimicrobial activity against propionibacterium acnes |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305778/ https://www.ncbi.nlm.nih.gov/pubmed/32587816 http://dx.doi.org/10.4103/japtr.JAPTR_1_20 |
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