Cargando…
Discovering small-molecule therapeutics against SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become a global health pandemic. The lack of effective treatments, coupled with its etiology, has resulted in more than 400,000 deaths at the time of writing. The SARS-CoV-2 genome is highly homologous to that of SARS-CoV, the...
Autores principales: | Tiwari, Vaibhav, Beer, Jacob C., Sankaranarayanan, Nehru Viji, Swanson-Mungerson, Michelle, Desai, Umesh R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305878/ https://www.ncbi.nlm.nih.gov/pubmed/32574699 http://dx.doi.org/10.1016/j.drudis.2020.06.017 |
Ejemplares similares
-
Preferential recognition and antagonism of SARS-CoV-2 spike glycoprotein binding to 3-O-sulfated heparan sulfate
por: Tiwari, Vaibhav, et al.
Publicado: (2020) -
A molecular dynamics-based algorithm for evaluating the glycosaminoglycan mimicking potential of synthetic, homogenous, sulfated small molecules
por: Nagarajan, Balaji, et al.
Publicado: (2017) -
On the Selectivity of Heparan Sulfate Recognition
by SARS-CoV-2 Spike Glycoprotein
por: Chittum, John E., et al.
Publicado: (2021) -
Combinatorial Virtual Library Screening Study of Transforming Growth Factor-β2–Chondroitin Sulfate System
por: Sankaranarayanan, Nehru Viji, et al.
Publicado: (2021) -
In-Depth Molecular Dynamics Study of All Possible Chondroitin Sulfate Disaccharides Reveals Key Insight into Structural Heterogeneity and Dynamism
por: Nagarajan, Balaji, et al.
Publicado: (2022)