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Fatal SARS-CoV-2 infection in a renal transplant recipient
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) caused a pandemic that first discovered in Wuhan, China. While 10% of the patients have asymptomatic infection, 15–20% have lung involvement, 5–10% have multiple organ failure, and macrophage activation syndrome. Chronic respiratory di...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305930/ https://www.ncbi.nlm.nih.gov/pubmed/32564306 http://dx.doi.org/10.1007/s13730-020-00496-4 |
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author | Dirim, Ahmet Burak Demir, Erol Ucar, Ali Riza Garayeva, Nurana Safak, Seda Oto, Ozgur Akin Yazici, Halil Alibeyoglu, Alpay Medet Orhun, Gunseli Cagatay, Arif Atahan Turkmen, Aydin |
author_facet | Dirim, Ahmet Burak Demir, Erol Ucar, Ali Riza Garayeva, Nurana Safak, Seda Oto, Ozgur Akin Yazici, Halil Alibeyoglu, Alpay Medet Orhun, Gunseli Cagatay, Arif Atahan Turkmen, Aydin |
author_sort | Dirim, Ahmet Burak |
collection | PubMed |
description | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) caused a pandemic that first discovered in Wuhan, China. While 10% of the patients have asymptomatic infection, 15–20% have lung involvement, 5–10% have multiple organ failure, and macrophage activation syndrome. Chronic respiratory diseases, diabetes mellitus, hypertension, and cancer are risk factors for mortality. Prognosis or optimal treatment strategy for renal transplant recipients in SARS-CoV-2 infection is still unknown. Besides fatal cases, there were also milder case reports. In addition, COVID-19 treatment and the maintenance immunosuppression strategy is still under debate. Antiviral therapies and drug interactions are special topics for these patients. To the best of our knowledge, favipiravir and anti-cytokine treatments have not been previously reported in a kidney transplant recipient with SARS-CoV-2 infection before. We report a case of SARS-CoV-2 infection in a kidney transplant recipient with fatal outcomes. |
format | Online Article Text |
id | pubmed-7305930 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Singapore |
record_format | MEDLINE/PubMed |
spelling | pubmed-73059302020-06-22 Fatal SARS-CoV-2 infection in a renal transplant recipient Dirim, Ahmet Burak Demir, Erol Ucar, Ali Riza Garayeva, Nurana Safak, Seda Oto, Ozgur Akin Yazici, Halil Alibeyoglu, Alpay Medet Orhun, Gunseli Cagatay, Arif Atahan Turkmen, Aydin CEN Case Rep Case Report The severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) caused a pandemic that first discovered in Wuhan, China. While 10% of the patients have asymptomatic infection, 15–20% have lung involvement, 5–10% have multiple organ failure, and macrophage activation syndrome. Chronic respiratory diseases, diabetes mellitus, hypertension, and cancer are risk factors for mortality. Prognosis or optimal treatment strategy for renal transplant recipients in SARS-CoV-2 infection is still unknown. Besides fatal cases, there were also milder case reports. In addition, COVID-19 treatment and the maintenance immunosuppression strategy is still under debate. Antiviral therapies and drug interactions are special topics for these patients. To the best of our knowledge, favipiravir and anti-cytokine treatments have not been previously reported in a kidney transplant recipient with SARS-CoV-2 infection before. We report a case of SARS-CoV-2 infection in a kidney transplant recipient with fatal outcomes. Springer Singapore 2020-06-20 /pmc/articles/PMC7305930/ /pubmed/32564306 http://dx.doi.org/10.1007/s13730-020-00496-4 Text en © Japanese Society of Nephrology 2020 |
spellingShingle | Case Report Dirim, Ahmet Burak Demir, Erol Ucar, Ali Riza Garayeva, Nurana Safak, Seda Oto, Ozgur Akin Yazici, Halil Alibeyoglu, Alpay Medet Orhun, Gunseli Cagatay, Arif Atahan Turkmen, Aydin Fatal SARS-CoV-2 infection in a renal transplant recipient |
title | Fatal SARS-CoV-2 infection in a renal transplant recipient |
title_full | Fatal SARS-CoV-2 infection in a renal transplant recipient |
title_fullStr | Fatal SARS-CoV-2 infection in a renal transplant recipient |
title_full_unstemmed | Fatal SARS-CoV-2 infection in a renal transplant recipient |
title_short | Fatal SARS-CoV-2 infection in a renal transplant recipient |
title_sort | fatal sars-cov-2 infection in a renal transplant recipient |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305930/ https://www.ncbi.nlm.nih.gov/pubmed/32564306 http://dx.doi.org/10.1007/s13730-020-00496-4 |
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