Combination of Dichloroacetate and Atorvastatin Regulates Excessive Proliferation and Oxidative Stress in Pulmonary Arterial Hypertension Development via p38 Signaling

Pulmonary arterial hypertension (PAH) is a lethal disease generally characterized by pulmonary artery remodeling. Mitochondrial metabolic disorders have been implicated as a critical regulator of excessively proliferative- and apoptosis-resistant phenotypes in pulmonary artery smooth muscle cells (P...

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Detalles Bibliográficos
Autores principales: Li, Tangzhiming, Li, Suqi, Feng, Yilu, Zeng, Xiaofang, Dong, Shaohong, Li, Jianghua, Zha, Lihuang, Luo, Hui, Zhao, Lin, Liu, Bin, Ou, Ziwei, Lin, Wenchao, Zhang, Mengqiu, Li, Sheng, Jiang, Qiuqiong, Qi, Qiangqiang, Xu, Qingyao, Yu, Zaixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306075/
https://www.ncbi.nlm.nih.gov/pubmed/32617141
http://dx.doi.org/10.1155/2020/6973636

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