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Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB1*04:01

T cells isolated from the pancreatic infiltrates of nonobese diabetic mice have been shown to recognize epitopes formed by the covalent cross-linking of proinsulin and secretory granule peptides. Formation of such hybrid insulin peptides (HIPs) was confirmed through mass spectrometry, and responses...

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Detalles Bibliográficos
Autores principales:	Arribas-Layton, David, Guyer, Perrin, Delong, Thomas, Dang, Mylinh, Chow, I-Ting, Speake, Cate, Greenbaum, Carla J., Kwok, William W., Baker, Rocky L., Haskins, Kathryn, James, Eddie A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2020
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306133/ https://www.ncbi.nlm.nih.gov/pubmed/32291282 http://dx.doi.org/10.2337/db19-0620

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