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Multiorgan failure following gastroenteritis: a case report
BACKGROUND: This report highlights the first published case of fatal septic shock associated with Clostridium perfringens and Enterococcus avium bacteremia due to infective gastroenteritis. CASE PRESENTATION: We report a case of hepatic infarction, abscess, and death following gastroenteritis in a 6...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306137/ https://www.ncbi.nlm.nih.gov/pubmed/32563263 http://dx.doi.org/10.1186/s13256-020-02402-z |
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author | De Zylva, Joseph Padley, James Badbess, Rassam Dedigama, Maneesha |
author_facet | De Zylva, Joseph Padley, James Badbess, Rassam Dedigama, Maneesha |
author_sort | De Zylva, Joseph |
collection | PubMed |
description | BACKGROUND: This report highlights the first published case of fatal septic shock associated with Clostridium perfringens and Enterococcus avium bacteremia due to infective gastroenteritis. CASE PRESENTATION: We report a case of hepatic infarction, abscess, and death following gastroenteritis in a 63-year-old Aboriginal man who initially presented to a rural hospital with suspected food poisoning. The patient had persistent fever and was commenced on empirical antibiotics. His blood culture results were positive for Clostridium perfringens and Enterococcus avium. He was transferred to a tertiary center but developed organ failure and refractory shock. Initial computed tomography of the abdomen was unremarkable, but repeat imaging showed small bowel enteritis, hepatic abscess, and infarction as a result of portal vein septic thromboembolism. Despite maximal intensive care treatment, including percutaneous drainage of hepatic abscess and broad antibiotic cover, the patient died 6 days after initial presentation. CONCLUSIONS: This case highlights the rare but commonly fatal course of sepsis associated with Clostridium perfringens bacteremia and demonstrates detrimental effects of coinfection with Enterococcus avium, including potential for rapidly seeding abscess formation. Lessons for rural practice are highlighted, including the need for urgent and early referral for intensive care support, particularly for patients with complex comorbidities. |
format | Online Article Text |
id | pubmed-7306137 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-73061372020-06-22 Multiorgan failure following gastroenteritis: a case report De Zylva, Joseph Padley, James Badbess, Rassam Dedigama, Maneesha J Med Case Rep Case Report BACKGROUND: This report highlights the first published case of fatal septic shock associated with Clostridium perfringens and Enterococcus avium bacteremia due to infective gastroenteritis. CASE PRESENTATION: We report a case of hepatic infarction, abscess, and death following gastroenteritis in a 63-year-old Aboriginal man who initially presented to a rural hospital with suspected food poisoning. The patient had persistent fever and was commenced on empirical antibiotics. His blood culture results were positive for Clostridium perfringens and Enterococcus avium. He was transferred to a tertiary center but developed organ failure and refractory shock. Initial computed tomography of the abdomen was unremarkable, but repeat imaging showed small bowel enteritis, hepatic abscess, and infarction as a result of portal vein septic thromboembolism. Despite maximal intensive care treatment, including percutaneous drainage of hepatic abscess and broad antibiotic cover, the patient died 6 days after initial presentation. CONCLUSIONS: This case highlights the rare but commonly fatal course of sepsis associated with Clostridium perfringens bacteremia and demonstrates detrimental effects of coinfection with Enterococcus avium, including potential for rapidly seeding abscess formation. Lessons for rural practice are highlighted, including the need for urgent and early referral for intensive care support, particularly for patients with complex comorbidities. BioMed Central 2020-06-21 /pmc/articles/PMC7306137/ /pubmed/32563263 http://dx.doi.org/10.1186/s13256-020-02402-z Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report De Zylva, Joseph Padley, James Badbess, Rassam Dedigama, Maneesha Multiorgan failure following gastroenteritis: a case report |
title | Multiorgan failure following gastroenteritis: a case report |
title_full | Multiorgan failure following gastroenteritis: a case report |
title_fullStr | Multiorgan failure following gastroenteritis: a case report |
title_full_unstemmed | Multiorgan failure following gastroenteritis: a case report |
title_short | Multiorgan failure following gastroenteritis: a case report |
title_sort | multiorgan failure following gastroenteritis: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306137/ https://www.ncbi.nlm.nih.gov/pubmed/32563263 http://dx.doi.org/10.1186/s13256-020-02402-z |
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