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Efficacy and safety of high-viscosity cement in percutaneous vertebroplasty for treatment of Osteoporotic vertebral compression fractures: A retrospective cohort study

To evaluate the efficacy and safety of high viscosity bone cement in the percutaneous vertebroplasty (PVP) for treatment of single-level osteoporotic vertebral compression fractures. Eighty patients were enrolled in this study. All patients were received PVP, and they were divided into 2 groups acco...

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Autores principales: Li, Kunpeng, Feng, Hongyong, Luo, Dawei, Zhang, Wen, Yang, Keshi, Ji, Changbin, Liu, Jinlong, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306342/
https://www.ncbi.nlm.nih.gov/pubmed/32502000
http://dx.doi.org/10.1097/MD.0000000000020515
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author Li, Kunpeng
Feng, Hongyong
Luo, Dawei
Zhang, Wen
Yang, Keshi
Ji, Changbin
Liu, Jinlong
Xu, Hui
author_facet Li, Kunpeng
Feng, Hongyong
Luo, Dawei
Zhang, Wen
Yang, Keshi
Ji, Changbin
Liu, Jinlong
Xu, Hui
author_sort Li, Kunpeng
collection PubMed
description To evaluate the efficacy and safety of high viscosity bone cement in the percutaneous vertebroplasty (PVP) for treatment of single-level osteoporotic vertebral compression fractures. Eighty patients were enrolled in this study. All patients were received PVP, and they were divided into 2 groups according to the viscosity of bone cement, either high viscosity bone cement (HV group) or low viscosity cement (LV group). Oswestry Disability Index questionnaire and visual analog scale as clinical assessments were quantified. The operative time and injected bone cement volume were recorded. The anterior vertebral height (AVH) and bone cement leakage were evaluated in the radiograph. No significant difference was observed in the operative time. Both groups showed significant improvements in pain relief and functional capacity status (visual analog scale and Oswestry disability index scores) after surgery. Less bone cement volume was injected into the the injured vertebra in the HV group and statistical significance was found between both groups. In the HV group, there was lower leakage rate and less patients of severe leakage compared with the LV group. However, the correction of AVH showed no significant differences between the 2 groups and no significant loss of AVH was observed in 2 groups. High-viscosity and low-viscosity PVP have the similar effects in improving quality of life and relieving pain. There were lower cement leakage rate and less patients of severe leakage in the PVP with high-viscosity bone cement.
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spelling pubmed-73063422020-07-08 Efficacy and safety of high-viscosity cement in percutaneous vertebroplasty for treatment of Osteoporotic vertebral compression fractures: A retrospective cohort study Li, Kunpeng Feng, Hongyong Luo, Dawei Zhang, Wen Yang, Keshi Ji, Changbin Liu, Jinlong Xu, Hui Medicine (Baltimore) 7100 To evaluate the efficacy and safety of high viscosity bone cement in the percutaneous vertebroplasty (PVP) for treatment of single-level osteoporotic vertebral compression fractures. Eighty patients were enrolled in this study. All patients were received PVP, and they were divided into 2 groups according to the viscosity of bone cement, either high viscosity bone cement (HV group) or low viscosity cement (LV group). Oswestry Disability Index questionnaire and visual analog scale as clinical assessments were quantified. The operative time and injected bone cement volume were recorded. The anterior vertebral height (AVH) and bone cement leakage were evaluated in the radiograph. No significant difference was observed in the operative time. Both groups showed significant improvements in pain relief and functional capacity status (visual analog scale and Oswestry disability index scores) after surgery. Less bone cement volume was injected into the the injured vertebra in the HV group and statistical significance was found between both groups. In the HV group, there was lower leakage rate and less patients of severe leakage compared with the LV group. However, the correction of AVH showed no significant differences between the 2 groups and no significant loss of AVH was observed in 2 groups. High-viscosity and low-viscosity PVP have the similar effects in improving quality of life and relieving pain. There were lower cement leakage rate and less patients of severe leakage in the PVP with high-viscosity bone cement. Wolters Kluwer Health 2020-06-05 /pmc/articles/PMC7306342/ /pubmed/32502000 http://dx.doi.org/10.1097/MD.0000000000020515 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 7100
Li, Kunpeng
Feng, Hongyong
Luo, Dawei
Zhang, Wen
Yang, Keshi
Ji, Changbin
Liu, Jinlong
Xu, Hui
Efficacy and safety of high-viscosity cement in percutaneous vertebroplasty for treatment of Osteoporotic vertebral compression fractures: A retrospective cohort study
title Efficacy and safety of high-viscosity cement in percutaneous vertebroplasty for treatment of Osteoporotic vertebral compression fractures: A retrospective cohort study
title_full Efficacy and safety of high-viscosity cement in percutaneous vertebroplasty for treatment of Osteoporotic vertebral compression fractures: A retrospective cohort study
title_fullStr Efficacy and safety of high-viscosity cement in percutaneous vertebroplasty for treatment of Osteoporotic vertebral compression fractures: A retrospective cohort study
title_full_unstemmed Efficacy and safety of high-viscosity cement in percutaneous vertebroplasty for treatment of Osteoporotic vertebral compression fractures: A retrospective cohort study
title_short Efficacy and safety of high-viscosity cement in percutaneous vertebroplasty for treatment of Osteoporotic vertebral compression fractures: A retrospective cohort study
title_sort efficacy and safety of high-viscosity cement in percutaneous vertebroplasty for treatment of osteoporotic vertebral compression fractures: a retrospective cohort study
topic 7100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306342/
https://www.ncbi.nlm.nih.gov/pubmed/32502000
http://dx.doi.org/10.1097/MD.0000000000020515
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