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Type II enteropathy-associated T cell lymphoma in the duodenum: A rare case report
INTRODUCTION: Enteropathy-associated T-cell lymphoma (EATL) is a very rare form of lymphoma in the gastrointestinal tract. The proximal jejunum and ileum are the most common sites of EATL, whereas EATL rarely arises in the duodenum, and EATL involving metastasis of the bilateral ovaries is even rare...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306349/ https://www.ncbi.nlm.nih.gov/pubmed/32501967 http://dx.doi.org/10.1097/MD.0000000000020050 |
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author | Liu, Zhicheng He, Liang Jiao, Yan Wang, Helei Suo, Jian |
author_facet | Liu, Zhicheng He, Liang Jiao, Yan Wang, Helei Suo, Jian |
author_sort | Liu, Zhicheng |
collection | PubMed |
description | INTRODUCTION: Enteropathy-associated T-cell lymphoma (EATL) is a very rare form of lymphoma in the gastrointestinal tract. The proximal jejunum and ileum are the most common sites of EATL, whereas EATL rarely arises in the duodenum, and EATL involving metastasis of the bilateral ovaries is even rarer. PATIENT CONCERNS: A 43-year-old female suffered from upper abdominal pain and weight loss for 3 months. DIAGNOSIS: Type II EATL. INTERVENTIONS: The patient was initially treated with chemotherapies, including 4 cycles of the CHOP-E and 2 cycles of the DHAP+ chidamide chemotherapy regimens. However, the patient did not respond well to chemotherapy. Surgical treatment of the duodenal obstruction, with perforation of small intestine and the duodenum, was performed successively. OUTCOMES: The patient died of septic shock only 1 day after the surgery for the second perforation. Her overall survival was 11 months from the time of initial diagnosis. CONCLUSION: This case suggests that EALT is highly invasive and its clinical course is very aggressive. Intestinal perforation, intestinal obstruction, or involvement of extraintestinal organs may occur in EALT patients. Additionally, EALT patients respond poorly to chemotherapy and have an extremely unfavorable prognosis. |
format | Online Article Text |
id | pubmed-7306349 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-73063492020-07-08 Type II enteropathy-associated T cell lymphoma in the duodenum: A rare case report Liu, Zhicheng He, Liang Jiao, Yan Wang, Helei Suo, Jian Medicine (Baltimore) 4800 INTRODUCTION: Enteropathy-associated T-cell lymphoma (EATL) is a very rare form of lymphoma in the gastrointestinal tract. The proximal jejunum and ileum are the most common sites of EATL, whereas EATL rarely arises in the duodenum, and EATL involving metastasis of the bilateral ovaries is even rarer. PATIENT CONCERNS: A 43-year-old female suffered from upper abdominal pain and weight loss for 3 months. DIAGNOSIS: Type II EATL. INTERVENTIONS: The patient was initially treated with chemotherapies, including 4 cycles of the CHOP-E and 2 cycles of the DHAP+ chidamide chemotherapy regimens. However, the patient did not respond well to chemotherapy. Surgical treatment of the duodenal obstruction, with perforation of small intestine and the duodenum, was performed successively. OUTCOMES: The patient died of septic shock only 1 day after the surgery for the second perforation. Her overall survival was 11 months from the time of initial diagnosis. CONCLUSION: This case suggests that EALT is highly invasive and its clinical course is very aggressive. Intestinal perforation, intestinal obstruction, or involvement of extraintestinal organs may occur in EALT patients. Additionally, EALT patients respond poorly to chemotherapy and have an extremely unfavorable prognosis. Wolters Kluwer Health 2020-06-05 /pmc/articles/PMC7306349/ /pubmed/32501967 http://dx.doi.org/10.1097/MD.0000000000020050 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 4800 Liu, Zhicheng He, Liang Jiao, Yan Wang, Helei Suo, Jian Type II enteropathy-associated T cell lymphoma in the duodenum: A rare case report |
title | Type II enteropathy-associated T cell lymphoma in the duodenum: A rare case report |
title_full | Type II enteropathy-associated T cell lymphoma in the duodenum: A rare case report |
title_fullStr | Type II enteropathy-associated T cell lymphoma in the duodenum: A rare case report |
title_full_unstemmed | Type II enteropathy-associated T cell lymphoma in the duodenum: A rare case report |
title_short | Type II enteropathy-associated T cell lymphoma in the duodenum: A rare case report |
title_sort | type ii enteropathy-associated t cell lymphoma in the duodenum: a rare case report |
topic | 4800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306349/ https://www.ncbi.nlm.nih.gov/pubmed/32501967 http://dx.doi.org/10.1097/MD.0000000000020050 |
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