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Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306454/ https://www.ncbi.nlm.nih.gov/pubmed/32606676 http://dx.doi.org/10.2147/IJN.S239548 |
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author | Wang, Yan Zhang, Yingru Cai, Gang Li, Qi |
author_facet | Wang, Yan Zhang, Yingru Cai, Gang Li, Qi |
author_sort | Wang, Yan |
collection | PubMed |
description | In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size. These characteristics guarantee that the exosomes can carry a wide range of tumor drugs, deliver the drug to the cancer, and reduce or eliminate the tumor drug band. The toxic side effects were significantly eliminated; meanwhile, the therapeutic effects of the drug on the tumor were remarkably improved. This paper reviewed the strategies and drugs presented by different scholars for the treatment of tumors based on the drugs carried by exosomes. |
format | Online Article Text |
id | pubmed-7306454 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-73064542020-06-29 Exosomes as Actively Targeted Nanocarriers for Cancer Therapy Wang, Yan Zhang, Yingru Cai, Gang Li, Qi Int J Nanomedicine Review In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size. These characteristics guarantee that the exosomes can carry a wide range of tumor drugs, deliver the drug to the cancer, and reduce or eliminate the tumor drug band. The toxic side effects were significantly eliminated; meanwhile, the therapeutic effects of the drug on the tumor were remarkably improved. This paper reviewed the strategies and drugs presented by different scholars for the treatment of tumors based on the drugs carried by exosomes. Dove 2020-06-17 /pmc/articles/PMC7306454/ /pubmed/32606676 http://dx.doi.org/10.2147/IJN.S239548 Text en © 2020 Wang et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Wang, Yan Zhang, Yingru Cai, Gang Li, Qi Exosomes as Actively Targeted Nanocarriers for Cancer Therapy |
title | Exosomes as Actively Targeted Nanocarriers for Cancer Therapy |
title_full | Exosomes as Actively Targeted Nanocarriers for Cancer Therapy |
title_fullStr | Exosomes as Actively Targeted Nanocarriers for Cancer Therapy |
title_full_unstemmed | Exosomes as Actively Targeted Nanocarriers for Cancer Therapy |
title_short | Exosomes as Actively Targeted Nanocarriers for Cancer Therapy |
title_sort | exosomes as actively targeted nanocarriers for cancer therapy |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306454/ https://www.ncbi.nlm.nih.gov/pubmed/32606676 http://dx.doi.org/10.2147/IJN.S239548 |
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