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Exosomes as Actively Targeted Nanocarriers for Cancer Therapy

In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Zhang, Yingru, Cai, Gang, Li, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306454/
https://www.ncbi.nlm.nih.gov/pubmed/32606676
http://dx.doi.org/10.2147/IJN.S239548
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author Wang, Yan
Zhang, Yingru
Cai, Gang
Li, Qi
author_facet Wang, Yan
Zhang, Yingru
Cai, Gang
Li, Qi
author_sort Wang, Yan
collection PubMed
description In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size. These characteristics guarantee that the exosomes can carry a wide range of tumor drugs, deliver the drug to the cancer, and reduce or eliminate the tumor drug band. The toxic side effects were significantly eliminated; meanwhile, the therapeutic effects of the drug on the tumor were remarkably improved. This paper reviewed the strategies and drugs presented by different scholars for the treatment of tumors based on the drugs carried by exosomes.
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spelling pubmed-73064542020-06-29 Exosomes as Actively Targeted Nanocarriers for Cancer Therapy Wang, Yan Zhang, Yingru Cai, Gang Li, Qi Int J Nanomedicine Review In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size. These characteristics guarantee that the exosomes can carry a wide range of tumor drugs, deliver the drug to the cancer, and reduce or eliminate the tumor drug band. The toxic side effects were significantly eliminated; meanwhile, the therapeutic effects of the drug on the tumor were remarkably improved. This paper reviewed the strategies and drugs presented by different scholars for the treatment of tumors based on the drugs carried by exosomes. Dove 2020-06-17 /pmc/articles/PMC7306454/ /pubmed/32606676 http://dx.doi.org/10.2147/IJN.S239548 Text en © 2020 Wang et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Wang, Yan
Zhang, Yingru
Cai, Gang
Li, Qi
Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
title Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
title_full Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
title_fullStr Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
title_full_unstemmed Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
title_short Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
title_sort exosomes as actively targeted nanocarriers for cancer therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306454/
https://www.ncbi.nlm.nih.gov/pubmed/32606676
http://dx.doi.org/10.2147/IJN.S239548
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