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Sinomenine Attenuates Acetaminophen-Induced Acute Liver Injury by Decreasing Oxidative Stress and Inflammatory Response via Regulating TGF-β/Smad Pathway in vitro and in vivo

INTRODUCTION: Liver disease is common and often life-threatening. Sinomenine (SIN) is an active ingredient extracted from Sinomenium acutum. This study investigated the protective effect and mechanism of sinomenine (SIN) on acetaminophen (APAP)-induced liver injury from in vitro and in vivo. METHOD...

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Detalles Bibliográficos
Autores principales:	Chen, Hui, Wang, Yao, Jiao, Fang-Zhou, Yang, Fan, Li, Xun, Wang, Lu-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306499/ https://www.ncbi.nlm.nih.gov/pubmed/32606606 http://dx.doi.org/10.2147/DDDT.S248823

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