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Colorectal neuroendocrine tumors: A case series

INTRODUCTION: Neuroendocrine tumors (NET) of the colon and sigmoid colon are uncommon compared to colorectal adenocarcinoma. Few reports have been made of NET of the colon and sigmoid colon that presents with peritonitis and large bowel obstruction. CASE PRESENTATION: Here, we report two cases of NE...

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Autores principales: Warsinggih, Liliyanto, Prihantono, Ariani, Gusti Deasy Wilda, Faruk, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306531/
https://www.ncbi.nlm.nih.gov/pubmed/32563832
http://dx.doi.org/10.1016/j.ijscr.2020.06.030
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author Warsinggih
Liliyanto
Prihantono
Ariani, Gusti Deasy Wilda
Faruk, Muhammad
author_facet Warsinggih
Liliyanto
Prihantono
Ariani, Gusti Deasy Wilda
Faruk, Muhammad
author_sort Warsinggih
collection PubMed
description INTRODUCTION: Neuroendocrine tumors (NET) of the colon and sigmoid colon are uncommon compared to colorectal adenocarcinoma. Few reports have been made of NET of the colon and sigmoid colon that presents with peritonitis and large bowel obstruction. CASE PRESENTATION: Here, we report two cases of NET of the colon and sigmoid colon, which were diagnosed and treated at our institution. In our first case, a 66-year-old man with a history of abdominal distension was diagnosed with NET via histopathology of the sigmoid colon. The second case involved a 45-year-old woman with the chief complaints of abdominal distention and inability to defecate; specimen histopathology of the descending colon showed neuroendocrine carcinoma features. Clinical outcome was very poor in our patients: eight months after the resection, the second patient demonstrated a sign of metastasis on the liver. CONCLUSION: An uncommon case of colon and sigmoid colon carcinoma with neuroendocrine and diagnostic difficulties precludes an exact description of the initial diagnostic criteria and management. Thus, our case series offers an overview of initial symptoms, radiological and histopathological features for early diagnosis, and proper management of NET.
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spelling pubmed-73065312020-06-25 Colorectal neuroendocrine tumors: A case series Warsinggih Liliyanto Prihantono Ariani, Gusti Deasy Wilda Faruk, Muhammad Int J Surg Case Rep Article INTRODUCTION: Neuroendocrine tumors (NET) of the colon and sigmoid colon are uncommon compared to colorectal adenocarcinoma. Few reports have been made of NET of the colon and sigmoid colon that presents with peritonitis and large bowel obstruction. CASE PRESENTATION: Here, we report two cases of NET of the colon and sigmoid colon, which were diagnosed and treated at our institution. In our first case, a 66-year-old man with a history of abdominal distension was diagnosed with NET via histopathology of the sigmoid colon. The second case involved a 45-year-old woman with the chief complaints of abdominal distention and inability to defecate; specimen histopathology of the descending colon showed neuroendocrine carcinoma features. Clinical outcome was very poor in our patients: eight months after the resection, the second patient demonstrated a sign of metastasis on the liver. CONCLUSION: An uncommon case of colon and sigmoid colon carcinoma with neuroendocrine and diagnostic difficulties precludes an exact description of the initial diagnostic criteria and management. Thus, our case series offers an overview of initial symptoms, radiological and histopathological features for early diagnosis, and proper management of NET. Elsevier 2020-06-12 /pmc/articles/PMC7306531/ /pubmed/32563832 http://dx.doi.org/10.1016/j.ijscr.2020.06.030 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Warsinggih
Liliyanto
Prihantono
Ariani, Gusti Deasy Wilda
Faruk, Muhammad
Colorectal neuroendocrine tumors: A case series
title Colorectal neuroendocrine tumors: A case series
title_full Colorectal neuroendocrine tumors: A case series
title_fullStr Colorectal neuroendocrine tumors: A case series
title_full_unstemmed Colorectal neuroendocrine tumors: A case series
title_short Colorectal neuroendocrine tumors: A case series
title_sort colorectal neuroendocrine tumors: a case series
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306531/
https://www.ncbi.nlm.nih.gov/pubmed/32563832
http://dx.doi.org/10.1016/j.ijscr.2020.06.030
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AT farukmuhammad colorectalneuroendocrinetumorsacaseseries