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Metformin Decreases Insulin Resistance in Type 1 Diabetes Through Regulating p53 and RAP2A in vitro and in vivo

PURPOSE: Patients with type 1 diabetes (T1D) are associated with a high risk of multiple complications, so the development of T1D treatment is urgently needed. This study was set out to explore the molecular mechanism of metformin in the treatment of T1D insulin resistance. PATIENTS AND METHODS: Sub...

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Detalles Bibliográficos
Autores principales:	Ren, Gao-Fei, Xiao, Li-Li, Ma, Xiao-Jun, Yan, Yu-Shan, Jiao, Peng-Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306576/ https://www.ncbi.nlm.nih.gov/pubmed/32606605 http://dx.doi.org/10.2147/DDDT.S249557

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