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Directed evolution approach to enhance efficiency and speed of outgrowth during single cell subcloning of Chinese Hamster Ovary cells

Chinese Hamster Ovary (CHO) cells are the working horse of the pharmaceutical industry. To obtain high producing cell clones and to satisfy regulatory requirements single cell cloning is a necessary step in cell line development. However, it is also a tedious, labor intensive and expensive process....

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Detalles Bibliográficos
Autores principales:	Weinguny, Marcus, Klanert, Gerald, Eisenhut, Peter, Jonsson, Andreas, Ivansson, Daniel, Lövgren, Ann, Borth, Nicole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306589/ https://www.ncbi.nlm.nih.gov/pubmed/32612755 http://dx.doi.org/10.1016/j.csbj.2020.05.020

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