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A new prodrug and bioactivity evaluation of methotrexate based on Chitosan
Methotrexate (MTX) is the most important drug used in the treatment of several kinds of cancers, such as colon cancer. However, this drug can cause a reduction in the target tissue bioavailability. It is administered orally and absorbed quickly. This study aimed to produce an anti-colon cancer prodr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306593/ https://www.ncbi.nlm.nih.gov/pubmed/32596525 http://dx.doi.org/10.1016/j.heliyon.2020.e04223 |