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Dynamic Evolution of De Novo DNA Methyltransferases in Rodent and Primate Genomes

Transcriptional silencing of retrotransposons via DNA methylation is paramount for mammalian fertility and reproductive fitness. During germ cell development, most mammalian species utilize the de novo DNA methyltransferases DNMT3A and DNMT3B to establish DNA methylation patterns. However, many rode...

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Detalles Bibliográficos
Autores principales:	Molaro, Antoine, Malik, Harmit S, Bourc’his, Deborah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Discoveries
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306680/ https://www.ncbi.nlm.nih.gov/pubmed/32077945 http://dx.doi.org/10.1093/molbev/msaa044

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