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Studies on the mechanism of general anesthesia
Inhaled anesthetics are a chemically diverse collection of hydrophobic molecules that robustly activate TWIK-related K(+) channels (TREK-1) and reversibly induce loss of consciousness. For 100 y, anesthetics were speculated to target cellular membranes, yet no plausible mechanism emerged to explain...
Autores principales: | Pavel, Mahmud Arif, Petersen, E. Nicholas, Wang, Hao, Lerner, Richard A., Hansen, Scott B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306821/ https://www.ncbi.nlm.nih.gov/pubmed/32467161 http://dx.doi.org/10.1073/pnas.2004259117 |
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