Generation of Transgenic Cynomolgus Monkeys Overexpressing the Gene for Amyloid-β Precursor Protein

Alzheimer’s disease (AD) is the most common cause of dementia and understanding its pathogenesis should lead to improved therapeutic and diagnostic methods. Although several groups have developed transgenic mouse models overexpressing the human amyloid-β precursor protein (APP) gene with AD mutation...

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Detalles Bibliográficos
Autores principales: Seita, Yasunari, Morimura, Toshifumi, Watanabe, Naoki, Iwatani, Chizuru, Tsuchiya, Hideaki, Nakamura, Shinichiro, Suzuki, Toshiharu, Yanagisawa, Daijiro, Tsukiyama, Tomoyuki, Nakaya, Masataka, Okamura, Eiichi, Muto, Masanaga, Ema, Masatsugu, Nishimura, Masaki, Tooyama, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306892/
https://www.ncbi.nlm.nih.gov/pubmed/32250299
http://dx.doi.org/10.3233/JAD-191081

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