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Cellular Gene Modulation of HIV-Infected CD4 T Cells in Response to Serial Treatment with the Histone Deacetylase Inhibitor Vorinostat

Histone deacetylase inhibitors (HDACi) are the most widely studied HIV latency-reversing agents (LRAs). The HDACi suberoylanilide hydroxamic acid (vorinostat [VOR]) has been employed in several clinical HIV latency reversal studies, as well as in vitro models of HIV latency, and has been shown to ef...

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Detalles Bibliográficos
Autores principales: Maxwell, Jill W., Falcinelli, Shane D., Nefedov, Alexey, Dorfmeier, Corin, Wu, Guoxin, Dewey, Morgan, Webber, Andrea L., Archin, Nancie M., Margolis, David M., Hazuda, Daria J., Barnard, Richard J. O., Howell, Bonnie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307144/
https://www.ncbi.nlm.nih.gov/pubmed/32295913
http://dx.doi.org/10.1128/JVI.00351-20

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