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Cellular Gene Modulation of HIV-Infected CD4 T Cells in Response to Serial Treatment with the Histone Deacetylase Inhibitor Vorinostat
Histone deacetylase inhibitors (HDACi) are the most widely studied HIV latency-reversing agents (LRAs). The HDACi suberoylanilide hydroxamic acid (vorinostat [VOR]) has been employed in several clinical HIV latency reversal studies, as well as in vitro models of HIV latency, and has been shown to ef...
Autores principales: | Maxwell, Jill W., Falcinelli, Shane D., Nefedov, Alexey, Dorfmeier, Corin, Wu, Guoxin, Dewey, Morgan, Webber, Andrea L., Archin, Nancie M., Margolis, David M., Hazuda, Daria J., Barnard, Richard J. O., Howell, Bonnie J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307144/ https://www.ncbi.nlm.nih.gov/pubmed/32295913 http://dx.doi.org/10.1128/JVI.00351-20 |
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