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Inferring Transmission Bottleneck Size from Viral Sequence Data Using a Novel Haplotype Reconstruction Method

The transmission bottleneck is defined as the number of viral particles that transmit from one host to establish an infection in another. Genome sequence data have been used to evaluate the size of the transmission bottleneck between humans infected with the influenza virus; however, the methods use...

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Detalles Bibliográficos
Autores principales:	Ghafari, Mahan, Lumby, Casper K., Weissman, Daniel B., Illingworth, Christopher J. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Genetic Diversity and Evolution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307158/ https://www.ncbi.nlm.nih.gov/pubmed/32295920 http://dx.doi.org/10.1128/JVI.00014-20

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