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Multisite SUMOylation restrains DNA polymerase η interactions with DNA damage sites

Translesion DNA synthesis (TLS) mediated by low-fidelity DNA polymerases is an essential cellular mechanism for bypassing DNA lesions that obstruct DNA replication progression. However, the access of TLS polymerases to the replication machinery must be kept tightly in check to avoid excessive mutage...

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Detalles Bibliográficos
Autores principales:	Guérillon, Claire, Smedegaard, Stine, Hendriks, Ivo A., Nielsen, Michael L., Mailand, Niels
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307195/ https://www.ncbi.nlm.nih.gov/pubmed/32350109 http://dx.doi.org/10.1074/jbc.RA120.013780

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