Putative functional variants of PI3K/AKT/mTOR pathway are associated with knee osteoarthritis susceptibility

BACKGROUND: Osteoarthritis (OA) is a degenerative musculoskeletal disease which causes joint deformity and pain and finally leads to limb dysfunction. Knee osteoarthritis (KOA) has the highest incidence among all kinds of OA. Strong evidence leads to the understanding that P13K/AKT/mTOR signaling is...

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Detalles Bibliográficos
Autores principales: Wang, Kejie, Chu, Minjie, Wang, Feng, Zhao, Yiwen, Chen, Haifeng, Dai, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307371/
https://www.ncbi.nlm.nih.gov/pubmed/32052902
http://dx.doi.org/10.1002/jcla.23240

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