False Rifampicin Resistance in Xpert Ultra Applied to Lymph Node Aspirate: A Case Report

A 36-year-old male patient was diagnosed with tuberculosis in Antwerp, Belgium, in May 2018. His lymph node aspirate initially tested rifampicin resistant in Xpert MTB/RIF Ultra, but tested susceptible in all other tests including targeted deep sequencing due to a rare matrix effect in the Xpert MTB...

Descripción completa

Detalles Bibliográficos
Autores principales: Ng, Kamela C S, Rigouts, Leen, de Jong, Bouke C, Lynen, Lutgarde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307434/
https://www.ncbi.nlm.nih.gov/pubmed/32607388
http://dx.doi.org/10.1093/ofid/ofaa204
_version_ 1783548808057061376
author Ng, Kamela C S
Rigouts, Leen
de Jong, Bouke C
Lynen, Lutgarde
author_facet Ng, Kamela C S
Rigouts, Leen
de Jong, Bouke C
Lynen, Lutgarde
author_sort Ng, Kamela C S
collection PubMed
description A 36-year-old male patient was diagnosed with tuberculosis in Antwerp, Belgium, in May 2018. His lymph node aspirate initially tested rifampicin resistant in Xpert MTB/RIF Ultra, but tested susceptible in all other tests including targeted deep sequencing due to a rare matrix effect in the Xpert MTB/RIF Ultra reaction tube.
format Online
Article
Text
id pubmed-7307434
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-73074342020-06-29 False Rifampicin Resistance in Xpert Ultra Applied to Lymph Node Aspirate: A Case Report Ng, Kamela C S Rigouts, Leen de Jong, Bouke C Lynen, Lutgarde Open Forum Infect Dis Brief Report A 36-year-old male patient was diagnosed with tuberculosis in Antwerp, Belgium, in May 2018. His lymph node aspirate initially tested rifampicin resistant in Xpert MTB/RIF Ultra, but tested susceptible in all other tests including targeted deep sequencing due to a rare matrix effect in the Xpert MTB/RIF Ultra reaction tube. Oxford University Press 2020-06-02 /pmc/articles/PMC7307434/ /pubmed/32607388 http://dx.doi.org/10.1093/ofid/ofaa204 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Ng, Kamela C S
Rigouts, Leen
de Jong, Bouke C
Lynen, Lutgarde
False Rifampicin Resistance in Xpert Ultra Applied to Lymph Node Aspirate: A Case Report
title False Rifampicin Resistance in Xpert Ultra Applied to Lymph Node Aspirate: A Case Report
title_full False Rifampicin Resistance in Xpert Ultra Applied to Lymph Node Aspirate: A Case Report
title_fullStr False Rifampicin Resistance in Xpert Ultra Applied to Lymph Node Aspirate: A Case Report
title_full_unstemmed False Rifampicin Resistance in Xpert Ultra Applied to Lymph Node Aspirate: A Case Report
title_short False Rifampicin Resistance in Xpert Ultra Applied to Lymph Node Aspirate: A Case Report
title_sort false rifampicin resistance in xpert ultra applied to lymph node aspirate: a case report
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307434/
https://www.ncbi.nlm.nih.gov/pubmed/32607388
http://dx.doi.org/10.1093/ofid/ofaa204
work_keys_str_mv AT ngkamelacs falserifampicinresistanceinxpertultraappliedtolymphnodeaspirateacasereport
AT rigoutsleen falserifampicinresistanceinxpertultraappliedtolymphnodeaspirateacasereport
AT dejongboukec falserifampicinresistanceinxpertultraappliedtolymphnodeaspirateacasereport
AT lynenlutgarde falserifampicinresistanceinxpertultraappliedtolymphnodeaspirateacasereport

Ejemplares similares