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Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2

BACKGROUND: Contaminated surfaces are a potential source for spread of respiratory viruses including SARS-CoV-2. Ultraviolet-C (UV-C) light is effective against RNA and DNA viruses and could be useful for decontamination of high-touch fomites that are shared by multiple users. METHODS: A modificatio...

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Autores principales: Cadnum, Jennifer L., Li, Daniel F., Jones, Lucas D., Redmond, Sarah N., Pearlmutter, Basya, Wilson, Brigid M., Donskey, Curtis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pathogens and Immunity 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307442/
https://www.ncbi.nlm.nih.gov/pubmed/32582873
http://dx.doi.org/10.20411/pai.v5i1.373
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author Cadnum, Jennifer L.
Li, Daniel F.
Jones, Lucas D.
Redmond, Sarah N.
Pearlmutter, Basya
Wilson, Brigid M.
Donskey, Curtis J.
author_facet Cadnum, Jennifer L.
Li, Daniel F.
Jones, Lucas D.
Redmond, Sarah N.
Pearlmutter, Basya
Wilson, Brigid M.
Donskey, Curtis J.
author_sort Cadnum, Jennifer L.
collection PubMed
description BACKGROUND: Contaminated surfaces are a potential source for spread of respiratory viruses including SARS-CoV-2. Ultraviolet-C (UV-C) light is effective against RNA and DNA viruses and could be useful for decontamination of high-touch fomites that are shared by multiple users. METHODS: A modification of the American Society for Testing and Materials standard quantitative carrier disk test method (ASTM E-2197-11) was used to examine the effectiveness of UV-C light for rapid decontamination of plastic airport security bins inoculated at 3 sites with methicillin-resistant Staphylococcus aureus (MRSA) and bacteriophages MS2, PhiX174, and Phi6, an enveloped RNA virus used as a surrogate for coronaviruses. Reductions of 3 log(10) on inoculated plastic bins were considered effective for decontamination. RESULTS: UV-C light administered as 10-, 20-, or 30-second cycles in proximity to a plastic bin reduced contamination on each of the test sites, including vertical and horizontal surfaces. The 30-second cycle met criteria for decontamination of all 3 test sites for all the test organisms except bacteriophage MS2 which was reduced by greater than 2 log(10) PFU at each site. CONCLUSIONS: UV-C light is an attractive technology for rapid decontamination of airport security bins. Further work is needed to evaluate the utility of UV-C light in real-world settings and to develop methods to provide automated movement of bins through a UV-C decontamination process.
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spelling pubmed-73074422020-06-23 Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2 Cadnum, Jennifer L. Li, Daniel F. Jones, Lucas D. Redmond, Sarah N. Pearlmutter, Basya Wilson, Brigid M. Donskey, Curtis J. Pathog Immun Research Article BACKGROUND: Contaminated surfaces are a potential source for spread of respiratory viruses including SARS-CoV-2. Ultraviolet-C (UV-C) light is effective against RNA and DNA viruses and could be useful for decontamination of high-touch fomites that are shared by multiple users. METHODS: A modification of the American Society for Testing and Materials standard quantitative carrier disk test method (ASTM E-2197-11) was used to examine the effectiveness of UV-C light for rapid decontamination of plastic airport security bins inoculated at 3 sites with methicillin-resistant Staphylococcus aureus (MRSA) and bacteriophages MS2, PhiX174, and Phi6, an enveloped RNA virus used as a surrogate for coronaviruses. Reductions of 3 log(10) on inoculated plastic bins were considered effective for decontamination. RESULTS: UV-C light administered as 10-, 20-, or 30-second cycles in proximity to a plastic bin reduced contamination on each of the test sites, including vertical and horizontal surfaces. The 30-second cycle met criteria for decontamination of all 3 test sites for all the test organisms except bacteriophage MS2 which was reduced by greater than 2 log(10) PFU at each site. CONCLUSIONS: UV-C light is an attractive technology for rapid decontamination of airport security bins. Further work is needed to evaluate the utility of UV-C light in real-world settings and to develop methods to provide automated movement of bins through a UV-C decontamination process. Pathogens and Immunity 2020-05-22 /pmc/articles/PMC7307442/ /pubmed/32582873 http://dx.doi.org/10.20411/pai.v5i1.373 Text en © Pathogens and Immunity 2020 This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Research Article
Cadnum, Jennifer L.
Li, Daniel F.
Jones, Lucas D.
Redmond, Sarah N.
Pearlmutter, Basya
Wilson, Brigid M.
Donskey, Curtis J.
Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2
title Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2
title_full Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2
title_fullStr Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2
title_full_unstemmed Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2
title_short Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2
title_sort evaluation of ultraviolet-c light for rapid decontamination of airport security bins in the era of sars-cov-2
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307442/
https://www.ncbi.nlm.nih.gov/pubmed/32582873
http://dx.doi.org/10.20411/pai.v5i1.373
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