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DAXX mediates high phosphate-induced endothelial cell apoptosis in vitro through activating ERK signaling

BACKGROUD AND PURPOSE: Hyperphosphatemia, which is a high inorganic phosphate (Pi) level in the serum, promotes endothelial cells dysfunction and is associated with cardiovascular diseases in patients with chronic kidney diseases (CKD). However, the underlying mechanism of high Pi-induced endothelia...

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Detalles Bibliográficos
Autores principales: Wang, Shu, Wu, Mingyu, Qin, Ling, Song, Yaxiang, Peng, Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307556/
https://www.ncbi.nlm.nih.gov/pubmed/32596036
http://dx.doi.org/10.7717/peerj.9203