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HIV Tat Protein Selectively Impairs CB(1) Receptor-Mediated Presynaptic Inhibition at Excitatory But Not Inhibitory Synapses

Despite the success of antiretroviral therapy in suppressing viral load, nearly half of the 37 million people infected with HIV experience cognitive and motor impairments, collectively classified as HIV-associated neurocognitive disorders (HAND). In the CNS, HIV-infected microglia release neurotoxic...

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Detalles Bibliográficos
Autores principales: Wu, Mariah M., Thayer, Stanley A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307634/
https://www.ncbi.nlm.nih.gov/pubmed/32471847
http://dx.doi.org/10.1523/ENEURO.0119-20.2020