Biomimetic reconstruction of the hematopoietic stem cell niche for in vitro amplification of human hematopoietic stem cells

Hematopoietic stem cell transplantation is successfully applied since the late 1950s; however, its efficacy still needs to be increased. A promising strategy is to transplant high numbers of pluripotent hematopoietic stem cells (HSCs). Therefore, an improved ex vivo culture system that supports prol...

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Detalles Bibliográficos
Autores principales: Marx-Blümel, L., Marx, C., Weise, F., Frey, J., Perner, B., Schlingloff, G., Lindig, N., Hampl, J., Sonnemann, J., Brauer, D., Voigt, A., Singh, S., Beck, B., Jäger, Ute-Maria, Wang, Z. Q., Beck, J. F., Schober, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307768/
https://www.ncbi.nlm.nih.gov/pubmed/32569325
http://dx.doi.org/10.1371/journal.pone.0234638

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