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Rotenone restrains colon cancer cell viability, motility and epithelial-mesenchymal transition and tumorigenesis in nude mice via the PI3K/AKT pathway

Rotenone, a natural hydrophobic pesticide, has been reported to display anticancer activity in a variety of cancer cells. However, the mechanism of rotenone on colon cancer (CC) cell migration, invasion and metastasis is still unknown. In the present study, the cytotoxicity of rotenone on CC cells w...

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Detalles Bibliográficos
Autores principales: Xiao, Wenbo, Liu, Yongwei, Dai, Maolin, Li, Yu, Peng, Renqun, Yu, Shuangjiang, Liu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307809/
https://www.ncbi.nlm.nih.gov/pubmed/32626924
http://dx.doi.org/10.3892/ijmm.2020.4637