Ursolic acid protects against cisplatin-induced ototoxicity by inhibiting oxidative stress and TRPV1-mediated Ca(2+)-signaling

Cisplatin (CDDP) is widely used in clinical settings for the treatment of various cancers. However, ototoxicity is a major side effect of CDDP, and there is an associated risk of irreversible hearing loss. We previously demonstrated that CDDP could induce ototoxicity via activation of the transient...

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Detalles Bibliográficos
Autores principales: Di, Yang, Xu, Tao, Tian, Yuan, Ma, Tingting, Qu, Donghao, Wang, Yan, Lin, Yuhan, Bao, Dongyan, Yu, Li, Liu, Shuangyue, Wang, Aimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307815/
https://www.ncbi.nlm.nih.gov/pubmed/32626955
http://dx.doi.org/10.3892/ijmm.2020.4633

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