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Is the tryptophan codon of gene vif the Achilles’ heel of HIV-1?
To evaluate the impact of hypermutation on the HIV-1 dissemination at the population level we studied 7072 sequences HIV-1 gene vif retrieved from the public databank. From this dataset 854 sequences were selected because they had associated values of CD4+ T lymphocytes counts and viral loads and th...
Autores principales: | Villanova, Fabiola, Barreiros, Marta, Leal, Élcio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308096/ https://www.ncbi.nlm.nih.gov/pubmed/32570272 http://dx.doi.org/10.1371/journal.pone.0225563 |
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