A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance

There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her seru...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahn, Byeong Yun, Kang, Chang Kyung, Seo, Jong Do, Choe, Pyoeng Gyun, Song, Sang Hoon, Park, Wan Beom, Park, Sang Won, Kim, Nam Joong, Oh, Myoung-don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308141/
https://www.ncbi.nlm.nih.gov/pubmed/32567262
http://dx.doi.org/10.3346/jkms.2020.35.e231
_version_ 1783548939439439872
author Ahn, Byeong Yun
Kang, Chang Kyung
Seo, Jong Do
Choe, Pyoeng Gyun
Song, Sang Hoon
Park, Wan Beom
Park, Sang Won
Kim, Nam Joong
Oh, Myoung-don
author_facet Ahn, Byeong Yun
Kang, Chang Kyung
Seo, Jong Do
Choe, Pyoeng Gyun
Song, Sang Hoon
Park, Wan Beom
Park, Sang Won
Kim, Nam Joong
Oh, Myoung-don
author_sort Ahn, Byeong Yun
collection PubMed
description There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 µg/L and 4,890 µg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.
format Online
Article
Text
id pubmed-7308141
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher The Korean Academy of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-73081412020-06-24 A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance Ahn, Byeong Yun Kang, Chang Kyung Seo, Jong Do Choe, Pyoeng Gyun Song, Sang Hoon Park, Wan Beom Park, Sang Won Kim, Nam Joong Oh, Myoung-don J Korean Med Sci Case Report There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 µg/L and 4,890 µg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19. The Korean Academy of Medical Sciences 2020-06-17 /pmc/articles/PMC7308141/ /pubmed/32567262 http://dx.doi.org/10.3346/jkms.2020.35.e231 Text en © 2020 The Korean Academy of Medical Sciences. https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ahn, Byeong Yun
Kang, Chang Kyung
Seo, Jong Do
Choe, Pyoeng Gyun
Song, Sang Hoon
Park, Wan Beom
Park, Sang Won
Kim, Nam Joong
Oh, Myoung-don
A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance
title A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance
title_full A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance
title_fullStr A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance
title_full_unstemmed A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance
title_short A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance
title_sort case of breakthrough covid-19 during hydroxychloroquine maintenance
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308141/
https://www.ncbi.nlm.nih.gov/pubmed/32567262
http://dx.doi.org/10.3346/jkms.2020.35.e231
work_keys_str_mv AT ahnbyeongyun acaseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT kangchangkyung acaseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT seojongdo acaseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT choepyoenggyun acaseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT songsanghoon acaseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT parkwanbeom acaseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT parksangwon acaseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT kimnamjoong acaseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT ohmyoungdon acaseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT ahnbyeongyun caseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT kangchangkyung caseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT seojongdo caseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT choepyoenggyun caseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT songsanghoon caseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT parkwanbeom caseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT parksangwon caseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT kimnamjoong caseofbreakthroughcovid19duringhydroxychloroquinemaintenance
AT ohmyoungdon caseofbreakthroughcovid19duringhydroxychloroquinemaintenance

Ejemplares similares