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Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer

Neoadjuvant chemotherapy is increasingly used in breast cancer, especially for downstaging the primary tumor in the breast and the metastatic axillary lymph node. Accurate evaluations of the response to neoadjuvant chemotherapy provide important information on the impact of systemic therapies on bre...

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Detalles Bibliográficos
Autores principales: Wang, Huan, Mao, Xiaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308147/
https://www.ncbi.nlm.nih.gov/pubmed/32606609
http://dx.doi.org/10.2147/DDDT.S253961
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author Wang, Huan
Mao, Xiaoyun
author_facet Wang, Huan
Mao, Xiaoyun
author_sort Wang, Huan
collection PubMed
description Neoadjuvant chemotherapy is increasingly used in breast cancer, especially for downstaging the primary tumor in the breast and the metastatic axillary lymph node. Accurate evaluations of the response to neoadjuvant chemotherapy provide important information on the impact of systemic therapies on breast cancer biology, prognosis, and guidance for further therapy. Moreover, pathologic complete response is a validated and valuable surrogate prognostic factor of survival after therapy. Evaluations of neoadjuvant chemotherapy response are very important in clinical work and basic research. In this review, we will elaborate on evaluations of the efficacy of neoadjuvant chemotherapy in breast cancer and provide a clinical evaluation procedure for neoadjuvant chemotherapy.
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spelling pubmed-73081472020-06-29 Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer Wang, Huan Mao, Xiaoyun Drug Des Devel Ther Review Neoadjuvant chemotherapy is increasingly used in breast cancer, especially for downstaging the primary tumor in the breast and the metastatic axillary lymph node. Accurate evaluations of the response to neoadjuvant chemotherapy provide important information on the impact of systemic therapies on breast cancer biology, prognosis, and guidance for further therapy. Moreover, pathologic complete response is a validated and valuable surrogate prognostic factor of survival after therapy. Evaluations of neoadjuvant chemotherapy response are very important in clinical work and basic research. In this review, we will elaborate on evaluations of the efficacy of neoadjuvant chemotherapy in breast cancer and provide a clinical evaluation procedure for neoadjuvant chemotherapy. Dove 2020-06-18 /pmc/articles/PMC7308147/ /pubmed/32606609 http://dx.doi.org/10.2147/DDDT.S253961 Text en © 2020 Wang and Mao. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Wang, Huan
Mao, Xiaoyun
Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer
title Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer
title_full Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer
title_fullStr Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer
title_full_unstemmed Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer
title_short Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer
title_sort evaluation of the efficacy of neoadjuvant chemotherapy for breast cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308147/
https://www.ncbi.nlm.nih.gov/pubmed/32606609
http://dx.doi.org/10.2147/DDDT.S253961
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