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Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer
Neoadjuvant chemotherapy is increasingly used in breast cancer, especially for downstaging the primary tumor in the breast and the metastatic axillary lymph node. Accurate evaluations of the response to neoadjuvant chemotherapy provide important information on the impact of systemic therapies on bre...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308147/ https://www.ncbi.nlm.nih.gov/pubmed/32606609 http://dx.doi.org/10.2147/DDDT.S253961 |
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author | Wang, Huan Mao, Xiaoyun |
author_facet | Wang, Huan Mao, Xiaoyun |
author_sort | Wang, Huan |
collection | PubMed |
description | Neoadjuvant chemotherapy is increasingly used in breast cancer, especially for downstaging the primary tumor in the breast and the metastatic axillary lymph node. Accurate evaluations of the response to neoadjuvant chemotherapy provide important information on the impact of systemic therapies on breast cancer biology, prognosis, and guidance for further therapy. Moreover, pathologic complete response is a validated and valuable surrogate prognostic factor of survival after therapy. Evaluations of neoadjuvant chemotherapy response are very important in clinical work and basic research. In this review, we will elaborate on evaluations of the efficacy of neoadjuvant chemotherapy in breast cancer and provide a clinical evaluation procedure for neoadjuvant chemotherapy. |
format | Online Article Text |
id | pubmed-7308147 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-73081472020-06-29 Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer Wang, Huan Mao, Xiaoyun Drug Des Devel Ther Review Neoadjuvant chemotherapy is increasingly used in breast cancer, especially for downstaging the primary tumor in the breast and the metastatic axillary lymph node. Accurate evaluations of the response to neoadjuvant chemotherapy provide important information on the impact of systemic therapies on breast cancer biology, prognosis, and guidance for further therapy. Moreover, pathologic complete response is a validated and valuable surrogate prognostic factor of survival after therapy. Evaluations of neoadjuvant chemotherapy response are very important in clinical work and basic research. In this review, we will elaborate on evaluations of the efficacy of neoadjuvant chemotherapy in breast cancer and provide a clinical evaluation procedure for neoadjuvant chemotherapy. Dove 2020-06-18 /pmc/articles/PMC7308147/ /pubmed/32606609 http://dx.doi.org/10.2147/DDDT.S253961 Text en © 2020 Wang and Mao. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Wang, Huan Mao, Xiaoyun Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer |
title | Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer |
title_full | Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer |
title_fullStr | Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer |
title_full_unstemmed | Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer |
title_short | Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer |
title_sort | evaluation of the efficacy of neoadjuvant chemotherapy for breast cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308147/ https://www.ncbi.nlm.nih.gov/pubmed/32606609 http://dx.doi.org/10.2147/DDDT.S253961 |
work_keys_str_mv | AT wanghuan evaluationoftheefficacyofneoadjuvantchemotherapyforbreastcancer AT maoxiaoyun evaluationoftheefficacyofneoadjuvantchemotherapyforbreastcancer |