Cargando…

Pro-death signaling of cytoprotective heat shock factor 1: upregulation of NOXA leading to apoptosis in heat-sensitive cells

Heat shock can induce either cytoprotective mechanisms or cell death. We found that in certain human and mouse cells, including spermatocytes, activated heat shock factor 1 (HSF1) binds to sequences located in the intron(s) of the PMAIP1 (NOXA) gene and upregulates its expression which induces apopt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Janus, Patryk, Toma-Jonik, Agnieszka, Vydra, Natalia, Mrowiec, Katarzyna, Korfanty, Joanna, Chadalski, Marek, Widłak, Piotr, Dudek, Karolina, Paszek, Anna, Rusin, Marek, Polańska, Joanna, Widłak, Wiesława
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308270/ https://www.ncbi.nlm.nih.gov/pubmed/31996779 http://dx.doi.org/10.1038/s41418-020-0501-8

Ejemplares similares

PHLDA1 Does Not Contribute Directly to Heat Shock-Induced Apoptosis of Spermatocytes
por: Janus, Patryk, et al.
Publicado: (2019)

Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia
por: Kus-Liśkiewicz, Małgorzata, et al.
Publicado: (2013)

17β-Estradiol Activates HSF1 via MAPK Signaling in ERα-Positive Breast Cancer Cells
por: Vydra, Natalia, et al.
Publicado: (2019)

HSF1 Can Prevent Inflammation following Heat Shock by Inhibiting the Excessive Activation of the ATF3 and JUN&FOS Genes
por: Janus, Patryk, et al.
Publicado: (2022)

Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells
por: Vydra, Natalia, et al.
Publicado: (2021)

An Increase in HSF1 Expression Directs Human Mammary Epithelial Cells toward a Mesenchymal Phenotype
por: Vydra, Natalia, et al.
Publicado: (2023)

Heat shock response regulates stimulus-specificity and sensitivity of the pro-inflammatory NF-κB signalling
por: Paszek, Anna, et al.
Publicado: (2020)

Overexpression of heat shock transcription factor 1 enhances the resistance of melanoma cells to doxorubicin and paclitaxel
por: Vydra, Natalia, et al.
Publicado: (2013)

Cross talk between cytokine and hyperthermia-induced pathways: identification of different subsets of NF-κB-dependent genes regulated by TNFα and heat shock
por: Janus, Patryk, et al.
Publicado: (2015)

Pleiotropic Role of HSF1 in Neoplastic Transformation
por: Vydra, Natalia, et al.
Publicado: (2014)

Quantitative analysis reveals crosstalk mechanisms of heat shock-induced attenuation of NF-κB signaling at the single cell level
por: Kardyńska, Małgorzata, et al.
Publicado: (2018)

RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation
por: Szołtysek, Katarzyna, et al.
Publicado: (2018)

Inhibition of the Heat Shock Protein A (HSPA) Family Potentiates the Anticancer Effects of Manumycin A
por: Sojka, Damian Robert, et al.
Publicado: (2021)

Cells and Viruses
por: Widłak, Wiesława
Publicado: (2013)

Signal Partitioning Algorithm for Highly Efficient Gaussian Mixture Modeling in Mass Spectrometry
por: Polanski, Andrzej, et al.
Publicado: (2015)

The Metabolic Footprint of Systemic Effects in the Blood Caused by Radiotherapy and Inflammatory Conditions: A Systematic Review
por: Jelonek, Karol, et al.
Publicado: (2023)

Biological Factors behind Melanoma Response to Immune Checkpoint Inhibitors
por: Olbryt, Magdalena, et al.
Publicado: (2020)

BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma
por: Rusinek, Dagmara, et al.
Publicado: (2015)

Serum Metabolite Profiles in Participants of Lung Cancer Screening Study; Comparison of Two Independent Cohorts
por: Widłak, Piotr, et al.
Publicado: (2021)

Aspirin Induced Glioma Apoptosis through Noxa Upregulation
por: Chang, Cheng-Yi, et al.
Publicado: (2020)

Heart irradiation reduces microvascular density and accumulation of HSPA1 in mice
por: Walaszczyk, Anna, et al.
Publicado: (2017)

Discrimination of normal oral mucosa from oral cancer by mass spectrometry imaging of proteins and lipids
por: Bednarczyk, Katarzyna, et al.
Publicado: (2018)

Reversible protein aggregation as cytoprotective mechanism against heat stress
por: Gallardo, Paola, et al.
Publicado: (2021)

Sorption of Heavy Metals by Sewage Sludge and Its Mixtures with Soil from Wastewater Treatment Plants Operating in MBR and INR Technology
por: Kowalik, Robert, et al.
Publicado: (2021)

The Lipid Composition of Serum-Derived Small Extracellular Vesicles in Participants of a Lung Cancer Screening Study
por: Smolarz, Mateusz, et al.
Publicado: (2021)

Mass spectrometry-based analysis of therapy-related changes in serum proteome patterns of patients with early-stage breast cancer
por: Pietrowska, Monika, et al.
Publicado: (2010)

Detection of molecular signatures of oral squamous cell carcinoma and normal epithelium – application of a novel methodology for unsupervised segmentation of imaging mass spectrometry data
por: Widlak, Piotr, et al.
Publicado: (2016)

Intra-Tumor Heterogeneity Revealed by Mass Spectrometry Imaging Is Associated with the Prognosis of Breast Cancer
por: Gawin, Marta, et al.
Publicado: (2021)

The cytoprotective sequestration activity of small heat shock proteins is evolutionarily conserved
por: Shrivastava, Aseem, et al.
Publicado: (2022)

Flavonoids and Mitochondria: Activation of Cytoprotective Pathways?
por: Kicinska, Anna, et al.
Publicado: (2020)

Partial-Body Irradiation in Patients with Prostate Cancer Treated with IMRT Has Little Effect on the Composition of Serum Proteome
por: Pietrowska, Monika, et al.
Publicado: (2015)

Ionizing radiation affects the composition of the proteome of extracellular vesicles released by head-and-neck cancer cells in vitro
por: Abramowicz, Agata, et al.
Publicado: (2019)

Cytoprotective Effects of Taurine on Heat-Induced Bovine Mammary Epithelial Cells In Vitro
por: Bai, Hui, et al.
Publicado: (2021)

Proteomic and Metabolomic Profiles of T Cell-Derived Exosomes Isolated from Human Plasma
por: Zebrowska, Aneta, et al.
Publicado: (2022)

Association of serum metabolome profile with the risk of breast cancer in participants of the HUNT2 study
por: Mrowiec, Katarzyna, et al.
Publicado: (2023)

Induction of Heat-Shock Protein 70 Expression by Geranylgeranylacetone Shows Cytoprotective Effects in Cardiomyocytes of Mice under Humid Heat Stress
por: Wang, Xiaowu, et al.
Publicado: (2014)

Radiotherapy-related changes in serum proteome patterns of head and neck cancer patients; the effect of low and medium doses of radiation delivered to large volumes of normal tissue
por: Widłak, Piotr, et al.
Publicado: (2013)

Identification of serum proteome signatures of locally advanced and metastatic gastric cancer: a pilot study
por: Abramowicz, Agata, et al.
Publicado: (2015)

Classification of Thyroid Tumors Based on Mass Spectrometry Imaging of Tissue Microarrays; a Single-Pixel Approach
por: Kurczyk, Agata, et al.
Publicado: (2020)

Systemic Effects of Radiotherapy and Concurrent Chemo-Radiotherapy in Head and Neck Cancer Patients—Comparison of Serum Metabolome Profiles
por: Jelonek, Karol, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3e6r3a0s1dao2iink25gds905r