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Cellular polyamines condense hyperphosphorylated Tau, triggering Alzheimer’s disease
Many gaps in our understanding of Alzheimer’s disease remain despite intense research efforts. One such prominent gap is the mechanism of Tau condensation and fibrillization. One viewpoint is that positively charged Tau is condensed by cytosolic polyanions. However, this hypothesis is likely based o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308275/ https://www.ncbi.nlm.nih.gov/pubmed/32572101 http://dx.doi.org/10.1038/s41598-020-67119-x |