Mapping CRISPR spaceromes reveals vast host-specific viromes of prokaryotes

CRISPR arrays contain spacers, some of which are homologous to genome segments of viruses and other parasitic genetic elements and are employed as portion of guide RNAs to recognize and specifically inactivate the target genomes. However, the fraction of the spacers in sequenced CRISPR arrays that r...

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Detalles Bibliográficos
Autores principales: Shmakov, Sergey A., Wolf, Yuri I., Savitskaya, Ekaterina, Severinov, Konstantin V., Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308287/
https://www.ncbi.nlm.nih.gov/pubmed/32572116
http://dx.doi.org/10.1038/s42003-020-1014-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308287/
https://www.ncbi.nlm.nih.gov/pubmed/32572116
http://dx.doi.org/10.1038/s42003-020-1014-1

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