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Mapping CRISPR spaceromes reveals vast host-specific viromes of prokaryotes
CRISPR arrays contain spacers, some of which are homologous to genome segments of viruses and other parasitic genetic elements and are employed as portion of guide RNAs to recognize and specifically inactivate the target genomes. However, the fraction of the spacers in sequenced CRISPR arrays that r...
Autores principales: | Shmakov, Sergey A., Wolf, Yuri I., Savitskaya, Ekaterina, Severinov, Konstantin V., Koonin, Eugene V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308287/ https://www.ncbi.nlm.nih.gov/pubmed/32572116 http://dx.doi.org/10.1038/s42003-020-1014-1 |
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