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Carbon nanoparticles induce endoplasmic reticulum stress around blood vessels with accumulation of misfolded proteins in the developing brain of offspring

Nano-particulate air pollution threatens developing brains and is epidemiologically related to neurodegenerative diseases involving deposition of misfolded proteins. However, the mechanism underlying developmental neurotoxicity by nanoparticles remains unknown. Here, we report that maternal exposure...

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Detalles Bibliográficos
Autores principales: Onoda, Atsuto, Kawasaki, Takayasu, Tsukiyama, Koichi, Takeda, Ken, Umezawa, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308306/
https://www.ncbi.nlm.nih.gov/pubmed/32572058
http://dx.doi.org/10.1038/s41598-020-66744-w