Catechol-O-methyltransferase rs4680 and rs4818 haplotype association with treatment response to olanzapine in patients with schizophrenia

Antipsychotic drugs target primarily dopaminergic system which makes catechol-O-methyltransferase (COMT) an interesting target in studies searching for treatment response predictors in schizophrenia. The study assessed the association of the COMT rs4680 and rs4818 polymorphisms with therapeutic resp...

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Detalles Bibliográficos
Autores principales: Nikolac Perkovic, Matea, Sagud, Marina, Zivkovic, Maja, Uzun, Suzana, Nedic Erjavec, Gordana, Kozumplik, Oliver, Svob Strac, Dubravka, Mimica, Ninoslav, Mihaljevic Peles, Alma, Pivac, Nela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308339/
https://www.ncbi.nlm.nih.gov/pubmed/32572118
http://dx.doi.org/10.1038/s41598-020-67351-5

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