Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH

Nonalcoholic fatty liver disease (NAFLD) and its evolution to inflammatory steatohepatitis (NASH) are the most common causes of chronic liver damage and transplantation that are reaching epidemic proportions due to the upraising incidence of metabolic syndrome, obesity, and diabetes. Currently, ther...

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Detalles Bibliográficos
Autores principales: Tan, Mingjun, Mosaoa, Rami, Graham, Garrett T., Kasprzyk-Pawelec, Anna, Gadre, Shreyas, Parasido, Erika, Catalina-Rodriguez, Olga, Foley, Patricia, Giaccone, Giuseppe, Cheema, Amrita, Kallakury, Bhaskar, Albanese, Chris, Yi, Chunling, Avantaggiati, Maria Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308387/
https://www.ncbi.nlm.nih.gov/pubmed/31959914
http://dx.doi.org/10.1038/s41418-020-0491-6

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