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A new safety index based on intrapulse monitoring of ultra-harmonic cavitation during ultrasound-induced blood-brain barrier opening procedures
Ultrasound-induced blood-brain barrier (BBB) opening using microbubbles is a promising technique for local delivery of therapeutic molecules into the brain. The real-time control of the ultrasound dose delivered through the skull is necessary as the range of pressure for efficient and safe BBB openi...
Autores principales: | Novell, A., Kamimura, H. A. S., Cafarelli, A., Gerstenmayer, M., Flament, J., Valette, J., Agou, P., Conti, A., Selingue, E., Aron Badin, R., Hantraye, P., Larrat, B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308405/ https://www.ncbi.nlm.nih.gov/pubmed/32572103 http://dx.doi.org/10.1038/s41598-020-66994-8 |
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