Novel EGFP reporter cell and mouse models for sensitive imaging and quantification of exon skipping

Duchenne muscular dystrophy (DMD) is a fatal X-linked disorder caused by nonsense or frameshift mutations in the DMD gene. Among various treatments available for DMD, antisense oligonucleotides (ASOs) mediated exon skipping is a promising therapeutic approach. For successful treatments, however, it...

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Detalles Bibliográficos
Autores principales: Hara, Yuko, Mizobe, Yoshitaka, Inoue, Yukiko U., Hashimoto, Yasumasa, Motohashi, Norio, Masaki, Yoshiaki, Seio, Kohji, Takeda, Shin’ichi, Nagata, Tetsuya, Wood, Matthew J. A., Inoue, Takayoshi, Aoki, Yoshitsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308408/
https://www.ncbi.nlm.nih.gov/pubmed/32572084
http://dx.doi.org/10.1038/s41598-020-67077-4

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