Cargando…
Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers
T follicular helper (T(FH)) cells are powerful regulators of affinity matured long-lived plasma cells. Eliciting protective, long-lasting antibody responses to achieve persistent immunity is the goal of most successful vaccines. Thus, there is potential in manipulating T(FH) cell responses. Herein,...
Autores principales: | Carnathan, Diane G., Kaushik, Kirti, Ellebedy, Ali H., Enemuo, Chiamaka A., Gebru, Etse H., Dhadvai, Pallavi, Rasheed, Mohammed Ata Ur, Pauthner, Matthias G., Ozorowski, Gabriel, Ahmed, Rafi, Burton, Dennis R., Ward, Andrew B., Silvestri, Guido, Crotty, Shane, Locci, Michela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308430/ https://www.ncbi.nlm.nih.gov/pubmed/32612608 http://dx.doi.org/10.3389/fimmu.2020.01213 |
Ejemplares similares
-
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques
por: Klasse, P. J., et al.
Publicado: (2018) -
Developability Assessment of Physicochemical Properties and Stability Profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 Envelope Glycoprotein Trimers as Candidate Vaccine Antigens
por: Whitaker, Neal, et al.
Publicado: (2019) -
Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization
por: Bianchi, Matteo, et al.
Publicado: (2018) -
cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV‐1 envelope glycoprotein vaccine candidate
por: Dey, Antu K., et al.
Publicado: (2017) -
Rapid Germinal Center and Antibody Responses in Non-human Primates
after a Single Nanoparticle Vaccine Immunization
por: Havenar-Daughton, Colin, et al.
Publicado: (2019)