Ectopic Atrial Tachycardia in a 12-Month-Old Girl Treated With Ivabradine and Beta-Blocker, a Case Report

We report on a 12-month-old girl with an ectopic atrial tachycardia successfully treated with the combination of a beta blocking agent and Ivabradine that acts on cardiac pacemaker cells by selectively inhibiting the I(f) channel. Standard therapy had failed to control the tachycardia before. No sid...

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Detalles Bibliográficos
Autores principales: Michel, Holger, Heißenhuber, Frank, Wellmann, Sven, Melter, Michael, Gerling, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308433/
https://www.ncbi.nlm.nih.gov/pubmed/32612966
http://dx.doi.org/10.3389/fped.2020.00313
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author Michel, Holger
Heißenhuber, Frank
Wellmann, Sven
Melter, Michael
Gerling, Stephan
author_facet Michel, Holger
Heißenhuber, Frank
Wellmann, Sven
Melter, Michael
Gerling, Stephan
author_sort Michel, Holger
collection PubMed
description We report on a 12-month-old girl with an ectopic atrial tachycardia successfully treated with the combination of a beta blocking agent and Ivabradine that acts on cardiac pacemaker cells by selectively inhibiting the I(f) channel. Standard therapy had failed to control the tachycardia before. No side effects attributable to Ivabradine were noticed. Due to its mechanism of action Ivabradine is a promising novel agent for the therapy of tachycardia due to increased automaticity. Reports on the use of Ivabradine in young children or infants are rare, but show promising results for congenital junctional ectopic tachycardia. This report adds the second case of ectopic atrial tachycardia in this age group and novel treatment with Ivabradine to the literature.
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spelling pubmed-73084332020-06-30 Ectopic Atrial Tachycardia in a 12-Month-Old Girl Treated With Ivabradine and Beta-Blocker, a Case Report Michel, Holger Heißenhuber, Frank Wellmann, Sven Melter, Michael Gerling, Stephan Front Pediatr Pediatrics We report on a 12-month-old girl with an ectopic atrial tachycardia successfully treated with the combination of a beta blocking agent and Ivabradine that acts on cardiac pacemaker cells by selectively inhibiting the I(f) channel. Standard therapy had failed to control the tachycardia before. No side effects attributable to Ivabradine were noticed. Due to its mechanism of action Ivabradine is a promising novel agent for the therapy of tachycardia due to increased automaticity. Reports on the use of Ivabradine in young children or infants are rare, but show promising results for congenital junctional ectopic tachycardia. This report adds the second case of ectopic atrial tachycardia in this age group and novel treatment with Ivabradine to the literature. Frontiers Media S.A. 2020-06-16 /pmc/articles/PMC7308433/ /pubmed/32612966 http://dx.doi.org/10.3389/fped.2020.00313 Text en Copyright © 2020 Michel, Heißenhuber, Wellmann, Melter and Gerling. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Michel, Holger
Heißenhuber, Frank
Wellmann, Sven
Melter, Michael
Gerling, Stephan
Ectopic Atrial Tachycardia in a 12-Month-Old Girl Treated With Ivabradine and Beta-Blocker, a Case Report
title Ectopic Atrial Tachycardia in a 12-Month-Old Girl Treated With Ivabradine and Beta-Blocker, a Case Report
title_full Ectopic Atrial Tachycardia in a 12-Month-Old Girl Treated With Ivabradine and Beta-Blocker, a Case Report
title_fullStr Ectopic Atrial Tachycardia in a 12-Month-Old Girl Treated With Ivabradine and Beta-Blocker, a Case Report
title_full_unstemmed Ectopic Atrial Tachycardia in a 12-Month-Old Girl Treated With Ivabradine and Beta-Blocker, a Case Report
title_short Ectopic Atrial Tachycardia in a 12-Month-Old Girl Treated With Ivabradine and Beta-Blocker, a Case Report
title_sort ectopic atrial tachycardia in a 12-month-old girl treated with ivabradine and beta-blocker, a case report
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308433/
https://www.ncbi.nlm.nih.gov/pubmed/32612966
http://dx.doi.org/10.3389/fped.2020.00313
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AT wellmannsven ectopicatrialtachycardiaina12montholdgirltreatedwithivabradineandbetablockeracasereport
AT meltermichael ectopicatrialtachycardiaina12montholdgirltreatedwithivabradineandbetablockeracasereport
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