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Independent Prognostic Value of Intratumoral Heterogeneity and Immune Response Features by Automated Digital Immunohistochemistry Analysis in Early Hormone Receptor-Positive Breast Carcinoma
Immunohistochemistry (IHC) for ER, PR, HER2, and Ki67 is used to predict outcome and therapy response in breast cancer patients. The current IHC assessment, visual or digital, is based mostly on global biomarker expression levels in the tissue sample. In our study, we explored the prognostic value o...
Autores principales: | Zilenaite, Dovile, Rasmusson, Allan, Augulis, Renaldas, Besusparis, Justinas, Laurinaviciene, Aida, Plancoulaine, Benoit, Ostapenko, Valerijus, Laurinavicius, Arvydas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308549/ https://www.ncbi.nlm.nih.gov/pubmed/32612954 http://dx.doi.org/10.3389/fonc.2020.00950 |
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