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Photocatalytic trifluoromethoxylation of arenes and heteroarenes in continuous-flow
The first example of photocatalytic trifluoromethoxylation of arenes and heteroarenes under continuous-flow conditions is described. Application of continuous-flow microreactor technology allowed to reduce the residence time up to 16 times in comparison to the batch procedure, while achieving simila...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308607/ https://www.ncbi.nlm.nih.gov/pubmed/32595778 http://dx.doi.org/10.3762/bjoc.16.111 |
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| author | Nyuchev, Alexander V Wan, Ting Cendón, Borja Sambiagio, Carlo Struijs, Job J C Ho, Michelle Gulías, Moisés Wang, Ying Noël, Timothy |
| author_facet | Nyuchev, Alexander V Wan, Ting Cendón, Borja Sambiagio, Carlo Struijs, Job J C Ho, Michelle Gulías, Moisés Wang, Ying Noël, Timothy |
| author_sort | Nyuchev, Alexander V |
| collection | PubMed |
| description | The first example of photocatalytic trifluoromethoxylation of arenes and heteroarenes under continuous-flow conditions is described. Application of continuous-flow microreactor technology allowed to reduce the residence time up to 16 times in comparison to the batch procedure, while achieving similar or higher yields. In addition, the use of inorganic bases was demonstrated to increase the reaction yield under batch conditions. |
| format | Online Article Text |
| id | pubmed-7308607 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-73086072020-06-25 Photocatalytic trifluoromethoxylation of arenes and heteroarenes in continuous-flow Nyuchev, Alexander V Wan, Ting Cendón, Borja Sambiagio, Carlo Struijs, Job J C Ho, Michelle Gulías, Moisés Wang, Ying Noël, Timothy Beilstein J Org Chem Full Research Paper The first example of photocatalytic trifluoromethoxylation of arenes and heteroarenes under continuous-flow conditions is described. Application of continuous-flow microreactor technology allowed to reduce the residence time up to 16 times in comparison to the batch procedure, while achieving similar or higher yields. In addition, the use of inorganic bases was demonstrated to increase the reaction yield under batch conditions. Beilstein-Institut 2020-06-15 /pmc/articles/PMC7308607/ /pubmed/32595778 http://dx.doi.org/10.3762/bjoc.16.111 Text en Copyright © 2020, Nyuchev et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Full Research Paper Nyuchev, Alexander V Wan, Ting Cendón, Borja Sambiagio, Carlo Struijs, Job J C Ho, Michelle Gulías, Moisés Wang, Ying Noël, Timothy Photocatalytic trifluoromethoxylation of arenes and heteroarenes in continuous-flow |
| title | Photocatalytic trifluoromethoxylation of arenes and heteroarenes in continuous-flow |
| title_full | Photocatalytic trifluoromethoxylation of arenes and heteroarenes in continuous-flow |
| title_fullStr | Photocatalytic trifluoromethoxylation of arenes and heteroarenes in continuous-flow |
| title_full_unstemmed | Photocatalytic trifluoromethoxylation of arenes and heteroarenes in continuous-flow |
| title_short | Photocatalytic trifluoromethoxylation of arenes and heteroarenes in continuous-flow |
| title_sort | photocatalytic trifluoromethoxylation of arenes and heteroarenes in continuous-flow |
| topic | Full Research Paper |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308607/ https://www.ncbi.nlm.nih.gov/pubmed/32595778 http://dx.doi.org/10.3762/bjoc.16.111 |
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