Cargando…

Interactions by Disorder – A Matter of Context

Living organisms depend on timely and organized interactions between proteins linked in interactomes of high complexity. The recent increased precision by which protein interactions can be studied, and the enclosure of intrinsic structural disorder, suggest that it is time to zoom out and embrace pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bugge, Katrine, Brakti, Inna, Fernandes, Catarina B., Dreier, Jesper E., Lundsgaard, Jeppe E., Olsen, Johan G., Skriver, Karen, Kragelund, Birthe B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308724/ https://www.ncbi.nlm.nih.gov/pubmed/32613009 http://dx.doi.org/10.3389/fmolb.2020.00110

Ejemplares similares

Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins
por: Newcombe, Estella A., et al.
Publicado: (2021)

Globular and disordered—the non-identical twins in protein-protein interactions
por: Teilum, Kaare, et al.
Publicado: (2015)

On the specificity of protein–protein interactions in the context of disorder
por: Teilum, Kaare, et al.
Publicado: (2021)

Ubiquitin Interacting Motifs: Duality Between Structured and Disordered Motifs
por: Lambrughi, Matteo, et al.
Publicado: (2021)

Refinement of α-Synuclein Ensembles Against SAXS Data: Comparison of Force Fields and Methods
por: Ahmed, Mustapha Carab, et al.
Publicado: (2021)

Evolutionary conservation of the intrinsic disorder-based Radical-Induced Cell Death1 hub interactome
por: Christensen, Lise Friis, et al.
Publicado: (2019)

Connecting the αα-hubs: same fold, disordered ligands, new functions
por: Staby, Lasse, et al.
Publicado: (2021)

αα-Hub domains and intrinsically disordered proteins: A decisive combo
por: Bugge, Katrine, et al.
Publicado: (2020)

Structure, dynamics, and stability of the globular domain of human linker histone H1.0 and the role of positive charges
por: Martinsen, Jacob H., et al.
Publicado: (2022)

Random coil chemical shifts for serine, threonine and tyrosine phosphorylation over a broad pH range
por: Hendus-Altenburger, Ruth, et al.
Publicado: (2019)

Glutamate Carrier Involvement in Mitochondrial Dysfunctioning in the Brain White Matter
por: Hillen, Anne E. J., et al.
Publicado: (2020)

Overview of methods for characterization and visualization of a protein–protein interaction network in a multi-omics integration context
por: Robin, Vivian, et al.
Publicado: (2022)

Aggregation is a Context-Dependent Constraint on Protein Evolution
por: Monti, Michele, et al.
Publicado: (2021)

The disordered PCI‐binding human proteins CSNAP and DSS1 have diverged in structure and function
por: Ruidiaz, Sarah F., et al.
Publicado: (2021)

High serum levels of the C-propetide of type V collagen (PRO-C5) are prognostic for short overall survival in patients with pancreatic ductal adenocarcinoma
por: Nissen, Neel I., et al.
Publicado: (2023)

Structural Context of a Critical Exon of Spinal Muscular Atrophy Gene
por: Singh, Natalia N., et al.
Publicado: (2022)

Casein Kinase 2 Signaling in White Matter Stroke
por: Nguyen, Hung, et al.
Publicado: (2022)

Antimicrobial activity of photosensitizers: arrangement in bacterial membrane matters
por: Batishchev, Oleg V., et al.
Publicado: (2023)

Processing of DNA Double-Strand Breaks by the MRX Complex in a Chromatin Context
por: Casari, Erika, et al.
Publicado: (2019)

Current Knowledge on the Role of Cardiolipin Remodeling in the Context of Lipid Oxidation and Barth Syndrome
por: Liang, Zhuqing, et al.
Publicado: (2022)

The Small Ones Matter—sHsps in the Bacterial Chaperone Network
por: Obuchowski, Igor, et al.
Publicado: (2021)

A Computational Solution to Automatically Map Metabolite Libraries in the Context of Genome Scale Metabolic Networks
por: Merlet, Benjamin, et al.
Publicado: (2016)

A Strategy for Functional Interpretation of Metabolomic Time Series Data in Context of Metabolic Network Information
por: Nägele, Thomas, et al.
Publicado: (2016)

The Transcription-Repair Coupling Factor Mfd Prevents and Promotes Mutagenesis in a Context-Dependent Manner
por: Lindsey-Boltz, Laura A., et al.
Publicado: (2021)

How phosphorylation impacts intrinsically disordered proteins and their function
por: Newcombe, Estella A., et al.
Publicado: (2022)

Toward Modeling Context-Specific EMT Regulatory Networks Using Temporal Single Cell RNA-Seq Data
por: Ramirez, Daniel, et al.
Publicado: (2020)

A Matter of Taste: Lineage-Specific Loss of Function of Taste Receptor Genes in Vertebrates
por: Antinucci, Marco, et al.
Publicado: (2017)

A context-dependent and disordered ubiquitin-binding motif
por: Dreier, Jesper E., et al.
Publicado: (2022)

3D Interaction Homology: Computational Titration of Aspartic Acid, Glutamic Acid and Histidine Can Create pH-Tunable Hydropathic Environment Maps
por: Herrington, Noah B., et al.
Publicado: (2021)

The Role of Indoor Plants in air Purification and Human Health in the Context of COVID-19 Pandemic: A Proposal for a Novel Line of Inquiry
por: El-Tanbouly, Rania, et al.
Publicado: (2021)

The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate
por: Araya-Secchi, Raul, et al.
Publicado: (2023)

Specificity of MYB interactions relies on motifs in ordered and disordered contexts
por: Millard, Peter S, et al.
Publicado: (2019)

Small Things Matter: The 11.6-kDa TraB Protein is Crucial for Antibiotic Resistance Transfer Among Enterococci
por: Berger, Tamara M.I., et al.
Publicado: (2022)

RNA-sequencing and mass-spectrometry proteomic time-series analysis of T-cell differentiation identified multiple splice variants models that predicted validated protein biomarkers in inflammatory diseases
por: Magnusson, Rasmus, et al.
Publicado: (2022)

Solution Structure of the dATP-Inactivated Class I Ribonucleotide Reductase From Leeuwenhoekiella blandensis by SAXS and Cryo-Electron Microscopy
por: Hasan, Mahmudul, et al.
Publicado: (2021)

3D interaction homology: The hydrophobic residues alanine, isoleucine, leucine, proline and valine play different structural roles in soluble and membrane proteins
por: AL Mughram, Mohammed H., et al.
Publicado: (2023)

Genomic reconstruction of short-chain fatty acid production by the human gut microbiota
por: Frolova, Maria S., et al.
Publicado: (2022)

Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design
por: Thomas, Sherine E., et al.
Publicado: (2022)

Blocking K-Ras Interaction With the Plasma Membrane Is a Tractable Therapeutic Approach to Inhibit Oncogenic K-Ras Activity
por: Henkels, Karen M., et al.
Publicado: (2021)

Aquaglyceroporin Modulators as Emergent Pharmacological Molecules for Human Diseases
por: Pimpão, Catarina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_302t4sk6lr152de8o6mbmefafe