Cargando…

Inhibition of Migration, Invasion and Drug Resistance of Pancreatic Adenocarcinoma Cells – Role of Snail, Slug and Twist and Small Molecule Inhibitors

PURPOSE: The main purpose of this study is to demonstrate the effects of epithelial to mesenchymal transition activating transcription factor silencing (EMT-ATF silencing) on migration, invasion, drug resistance and tumor-forming abilities of various pancreatic cancer cell lines. Additionally, the c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaşıkcı, Ezgi, Aydemir, Esra, Bayrak, Ömer Faruk, Şahin, Fikrettin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308789/ https://www.ncbi.nlm.nih.gov/pubmed/32606788 http://dx.doi.org/10.2147/OTT.S253418

Ejemplares similares

E-cadherin might be a stage-dependent modulator in aggressiveness in pancreatic cancer cells
por: AYDEMİR ÇOBAN, Esra, et al.
Publicado: (2020)

Inhibition of Migration, Invasion and Drug Resistance of Pancreatic Adenocarcinoma Cells – Role of Snail, Slug and Twist and Small Molecule Inhibitors [Corrigendum]
Publicado: (2022)

Expression of transcription factors snail, slug, and twist in human bladder carcinoma
por: Yu, Qinchao, et al.
Publicado: (2010)

Expression of Twist, Slug and Snail in esophageal squamous cell carcinoma and their prognostic significance
por: Xu, Shanshan, et al.
Publicado: (2021)

Cordycepin Inhibits Triple-Negative Breast Cancer Cell Migration and Invasion by Regulating EMT-TFs SLUG, TWIST1, SNAIL1, and ZEB1
por: Wei, Chunli, et al.
Publicado: (2022)

Experimental indications of gardeners’ anecdotes that snails interfere with invasive slugs
por: Dörler, Daniel, et al.
Publicado: (2021)

The F-box protein Ppa is a common regulator of core EMT factors Twist, Snail, Slug, and Sip1
por: Lander, Rachel, et al.
Publicado: (2011)

The epithelial–mesenchymal transition regulators Twist, Slug, and Snail are associated with aggressive tumour features and poor outcome in prostate cancer patients
por: Børretzen, Astrid, et al.
Publicado: (2021)

Relevance and prognostic ability of Twist, Slug and tumor spread through air spaces in lung adenocarcinoma
por: Liu, Ao, et al.
Publicado: (2020)

Biological activities of gastropods secretions: snail and slug slime
por: Rashad, Muhammad, et al.
Publicado: (2023)

Slug, Twist, and E-Cadherin as Immunohistochemical Biomarkers in Meningeal Tumors
por: Nagaishi, Masaya, et al.
Publicado: (2012)

Reciprocal expression of Slug and Snail in human oral cancer cells
por: Nakamura, Ryosuke, et al.
Publicado: (2018)

Pancreatic cancer SLUGged
por: Josselsohn, Rachel H., et al.
Publicado: (2020)

Ringiculid bubble snails recovered as the sister group to sea slugs (Nudipleura)
por: Kano, Yasunori, et al.
Publicado: (2016)

SLUG and SNAIL as Potential Immunohistochemical Biomarkers for Renal Cancer Staging and Survival
por: Zivotic, Maja, et al.
Publicado: (2023)

Leukemia Inhibitory Factor Promotes Aggressiveness of Chordoma
por: Gulluoglu, Sukru, et al.
Publicado: (2017)

DEPDC1B promotes migration and invasion in pancreatic ductal adenocarcinoma by activating the Akt/GSK3β/Snail pathway
por: Liu, Xu, et al.
Publicado: (2020)

AP-2β inhibits hepatocellular carcinoma invasion and metastasis through Slug and Snail to suppress epithelial-mesenchymal transition
por: Yang, Liu, et al.
Publicado: (2018)

EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer
por: Haslehurst, Alexandria M, et al.
Publicado: (2012)

The Hedgehog/GLI signaling pathway activates transcription of Slug (Snail2) in melanoma cells
por: Horák, Pavel, et al.
Publicado: (2023)

Actinomycin V Inhibits Migration and Invasion via Suppressing Snail/Slug-Mediated Epithelial-Mesenchymal Transition Progression in Human Breast Cancer MDA-MB-231 Cells In Vitro
por: Lin, Shiqi, et al.
Publicado: (2019)

The investigation of diverse physiological and therapeutic impact of cellular-based products derived from human cumulus cells
por: BURUKÇU, Derya, et al.
Publicado: (2022)

The TWIST1-centered competing endogenous RNA network promotes proliferation, invasion, and migration of lung adenocarcinoma
por: Xia, Wenjie, et al.
Publicado: (2019)

Twist expression promotes migration and invasion in hepatocellular carcinoma
por: Matsuo, Noriyuki, et al.
Publicado: (2009)

Snail/Slug-YAP/TAZ Complexes Control Skeletal Stem Cell Self-Renewal and Differentiation
por: Tang, Yi, et al.
Publicado: (2016)

Fermenting Bread Dough as a Cheap, Effective, Nontoxic, and Generic Attractant for Pest Snails and Slugs
por: Veasey, Robin, et al.
Publicado: (2021)

Origin and significance of two pairs of head tentacles in the radiation of euthyneuran sea slugs and land snails
por: Brenzinger, Bastian, et al.
Publicado: (2021)

TGIF1-Twist1 axis in pancreatic ductal adenocarcinoma
por: Razzaque, Mohammed S., et al.
Publicado: (2020)

Stabilization of the transcription factors slug and twist by the deubiquitinase dub3 is a key requirement for tumor metastasis
por: Lin, Yiwei, et al.
Publicado: (2017)

The Transcription Factors Snail and Slug Activate the Transforming Growth Factor-Beta Signaling Pathway in Breast Cancer
por: Dhasarathy, Archana, et al.
Publicado: (2011)

Land snails and slugs of Bau limestone hills, Sarawak (Malaysia, Borneo), with the descriptions of 13 new species
por: Marzuki, Mohammad Effendi bin, et al.
Publicado: (2021)

SLUG Manual - SLUG Interface to GEANT
por: DeWolf, R S
Publicado: (1993)

Analysis of Snail1 function and regulation by Twist1 in palatal fusion
por: Yu, Wenli, et al.
Publicado: (2013)

SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis
por: Uygur, Berna, et al.
Publicado: (2011)

MiRNA-203 suppresses tumor cell proliferation, migration and invasion by targeting Slug in gastric cancer
por: Yang, Liuqing, et al.
Publicado: (2016)

Pellino-1 promotes lung carcinogenesis via the stabilization of Slug and Snail through K63-mediated polyubiquitination
por: Jeon, Yoon Kyung, et al.
Publicado: (2017)

FOXM1 Promotes Lung Adenocarcinoma Invasion and Metastasis by Upregulating SNAIL
por: Wei, Ping, et al.
Publicado: (2015)

DLX4 Upregulates TWIST and Enhances Tumor Migration, Invasion and Metastasis
por: Zhang, Lianmei, et al.
Publicado: (2012)

Corrigendum to: The transcription factors slug (SNAI2) and snail (SNAI1) regulate phospholipase D (PLD) promoter in opposite ways towards cancer cell invasion
Publicado: (2023)

MDA-9/Syntenin-Slug transcriptional complex promote epithelial-mesenchymal transition and invasion/metastasis in lung adenocarcinoma
por: Wang, Lu-Kai, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_f93dpjtsddnuu46ta5bp37chsf