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Ultrasensitive Surface Plasmon Resonance Biosensor Using Blue Phosphorus–Graphene Architecture

This study theoretically proposed a novel surface plasmon resonance biosensor by incorporating emerging two dimensional material blue phosphorus and graphene layers with plasmonic gold film. The excellent performances employed for biosensing can be realized by accurately tuning the thickness of gold...

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Detalles Bibliográficos
Autores principales: Li, Keyi, Li, Lintong, Xu, Nanlin, Peng, Xiao, Zhou, Yingxin, Yuan, Yufeng, Song, Jun, Qu, Junle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308865/
https://www.ncbi.nlm.nih.gov/pubmed/32545230
http://dx.doi.org/10.3390/s20113326
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author Li, Keyi
Li, Lintong
Xu, Nanlin
Peng, Xiao
Zhou, Yingxin
Yuan, Yufeng
Song, Jun
Qu, Junle
author_facet Li, Keyi
Li, Lintong
Xu, Nanlin
Peng, Xiao
Zhou, Yingxin
Yuan, Yufeng
Song, Jun
Qu, Junle
author_sort Li, Keyi
collection PubMed
description This study theoretically proposed a novel surface plasmon resonance biosensor by incorporating emerging two dimensional material blue phosphorus and graphene layers with plasmonic gold film. The excellent performances employed for biosensing can be realized by accurately tuning the thickness of gold film and the number of blue phosphorus interlayer. Our proposed plasmonic biosensor architecture designed by phase modulation is much superior to angular modulation, providing 4 orders of magnitude sensitivity enhancement. In addition, the optimized stacked configuration is 42 nm Au film/2-layer blue phosphorus /4-layer graphene, which can produce the sharpest differential phase of 176.7661 degrees and darkest minimum reflectivity as low as 5.3787 × 10(−6). For a tiny variation in local refractive index of 0.0012 RIU (RIU, refractive index unit) due to the binding interactions of aromatic biomolecules, our proposed biosensor can provide an ultrahigh detection sensitivity up to 1.4731 × 10(5) °/RIU, highly promising for performing ultrasensitive biosensing application.
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spelling pubmed-73088652020-06-25 Ultrasensitive Surface Plasmon Resonance Biosensor Using Blue Phosphorus–Graphene Architecture Li, Keyi Li, Lintong Xu, Nanlin Peng, Xiao Zhou, Yingxin Yuan, Yufeng Song, Jun Qu, Junle Sensors (Basel) Letter This study theoretically proposed a novel surface plasmon resonance biosensor by incorporating emerging two dimensional material blue phosphorus and graphene layers with plasmonic gold film. The excellent performances employed for biosensing can be realized by accurately tuning the thickness of gold film and the number of blue phosphorus interlayer. Our proposed plasmonic biosensor architecture designed by phase modulation is much superior to angular modulation, providing 4 orders of magnitude sensitivity enhancement. In addition, the optimized stacked configuration is 42 nm Au film/2-layer blue phosphorus /4-layer graphene, which can produce the sharpest differential phase of 176.7661 degrees and darkest minimum reflectivity as low as 5.3787 × 10(−6). For a tiny variation in local refractive index of 0.0012 RIU (RIU, refractive index unit) due to the binding interactions of aromatic biomolecules, our proposed biosensor can provide an ultrahigh detection sensitivity up to 1.4731 × 10(5) °/RIU, highly promising for performing ultrasensitive biosensing application. MDPI 2020-06-11 /pmc/articles/PMC7308865/ /pubmed/32545230 http://dx.doi.org/10.3390/s20113326 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Letter
Li, Keyi
Li, Lintong
Xu, Nanlin
Peng, Xiao
Zhou, Yingxin
Yuan, Yufeng
Song, Jun
Qu, Junle
Ultrasensitive Surface Plasmon Resonance Biosensor Using Blue Phosphorus–Graphene Architecture
title Ultrasensitive Surface Plasmon Resonance Biosensor Using Blue Phosphorus–Graphene Architecture
title_full Ultrasensitive Surface Plasmon Resonance Biosensor Using Blue Phosphorus–Graphene Architecture
title_fullStr Ultrasensitive Surface Plasmon Resonance Biosensor Using Blue Phosphorus–Graphene Architecture
title_full_unstemmed Ultrasensitive Surface Plasmon Resonance Biosensor Using Blue Phosphorus–Graphene Architecture
title_short Ultrasensitive Surface Plasmon Resonance Biosensor Using Blue Phosphorus–Graphene Architecture
title_sort ultrasensitive surface plasmon resonance biosensor using blue phosphorus–graphene architecture
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308865/
https://www.ncbi.nlm.nih.gov/pubmed/32545230
http://dx.doi.org/10.3390/s20113326
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