Cargando…
Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors
Pd(0)-catalyzed amination was employed for the synthesis of a new family of (S)-1,1′-bianaphthalene-2,2′-diamine derivatives possessing additional chiral and fluorophore substituents. The Compounds thus obtained were tested as potential detectors of seven amino alcohols, and some of them were found...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308982/ https://www.ncbi.nlm.nih.gov/pubmed/32517228 http://dx.doi.org/10.3390/s20113234 |
_version_ | 1783549118127276032 |
---|---|
author | Shaferov, Alexander V. Malysheva, Anna S. Averin, Alexei D. Maloshitskaya, Olga A. Beletskaya, Irina P. |
author_facet | Shaferov, Alexander V. Malysheva, Anna S. Averin, Alexei D. Maloshitskaya, Olga A. Beletskaya, Irina P. |
author_sort | Shaferov, Alexander V. |
collection | PubMed |
description | Pd(0)-catalyzed amination was employed for the synthesis of a new family of (S)-1,1′-bianaphthalene-2,2′-diamine derivatives possessing additional chiral and fluorophore substituents. The Compounds thus obtained were tested as potential detectors of seven amino alcohols, and some of them were found to be able to recognize individual enantiomers of certain amino alcohols by specific changes of their emission spectra in the presence of these analytes. A pronounced dependence of the detecting abilities on the nature of the substituents in the (S)-BINAM derivatives was observed. |
format | Online Article Text |
id | pubmed-7308982 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-73089822020-06-25 Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors Shaferov, Alexander V. Malysheva, Anna S. Averin, Alexei D. Maloshitskaya, Olga A. Beletskaya, Irina P. Sensors (Basel) Article Pd(0)-catalyzed amination was employed for the synthesis of a new family of (S)-1,1′-bianaphthalene-2,2′-diamine derivatives possessing additional chiral and fluorophore substituents. The Compounds thus obtained were tested as potential detectors of seven amino alcohols, and some of them were found to be able to recognize individual enantiomers of certain amino alcohols by specific changes of their emission spectra in the presence of these analytes. A pronounced dependence of the detecting abilities on the nature of the substituents in the (S)-BINAM derivatives was observed. MDPI 2020-06-06 /pmc/articles/PMC7308982/ /pubmed/32517228 http://dx.doi.org/10.3390/s20113234 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Shaferov, Alexander V. Malysheva, Anna S. Averin, Alexei D. Maloshitskaya, Olga A. Beletskaya, Irina P. Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors |
title | Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors |
title_full | Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors |
title_fullStr | Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors |
title_full_unstemmed | Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors |
title_short | Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors |
title_sort | synthesis and evaluation of the (s)-binam derivatives as fluorescent enantioselective detectors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308982/ https://www.ncbi.nlm.nih.gov/pubmed/32517228 http://dx.doi.org/10.3390/s20113234 |
work_keys_str_mv | AT shaferovalexanderv synthesisandevaluationofthesbinamderivativesasfluorescentenantioselectivedetectors AT malyshevaannas synthesisandevaluationofthesbinamderivativesasfluorescentenantioselectivedetectors AT averinalexeid synthesisandevaluationofthesbinamderivativesasfluorescentenantioselectivedetectors AT maloshitskayaolgaa synthesisandevaluationofthesbinamderivativesasfluorescentenantioselectivedetectors AT beletskayairinap synthesisandevaluationofthesbinamderivativesasfluorescentenantioselectivedetectors |