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Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors

Pd(0)-catalyzed amination was employed for the synthesis of a new family of (S)-1,1′-bianaphthalene-2,2′-diamine derivatives possessing additional chiral and fluorophore substituents. The Compounds thus obtained were tested as potential detectors of seven amino alcohols, and some of them were found...

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Autores principales: Shaferov, Alexander V., Malysheva, Anna S., Averin, Alexei D., Maloshitskaya, Olga A., Beletskaya, Irina P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308982/
https://www.ncbi.nlm.nih.gov/pubmed/32517228
http://dx.doi.org/10.3390/s20113234
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author Shaferov, Alexander V.
Malysheva, Anna S.
Averin, Alexei D.
Maloshitskaya, Olga A.
Beletskaya, Irina P.
author_facet Shaferov, Alexander V.
Malysheva, Anna S.
Averin, Alexei D.
Maloshitskaya, Olga A.
Beletskaya, Irina P.
author_sort Shaferov, Alexander V.
collection PubMed
description Pd(0)-catalyzed amination was employed for the synthesis of a new family of (S)-1,1′-bianaphthalene-2,2′-diamine derivatives possessing additional chiral and fluorophore substituents. The Compounds thus obtained were tested as potential detectors of seven amino alcohols, and some of them were found to be able to recognize individual enantiomers of certain amino alcohols by specific changes of their emission spectra in the presence of these analytes. A pronounced dependence of the detecting abilities on the nature of the substituents in the (S)-BINAM derivatives was observed.
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spelling pubmed-73089822020-06-25 Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors Shaferov, Alexander V. Malysheva, Anna S. Averin, Alexei D. Maloshitskaya, Olga A. Beletskaya, Irina P. Sensors (Basel) Article Pd(0)-catalyzed amination was employed for the synthesis of a new family of (S)-1,1′-bianaphthalene-2,2′-diamine derivatives possessing additional chiral and fluorophore substituents. The Compounds thus obtained were tested as potential detectors of seven amino alcohols, and some of them were found to be able to recognize individual enantiomers of certain amino alcohols by specific changes of their emission spectra in the presence of these analytes. A pronounced dependence of the detecting abilities on the nature of the substituents in the (S)-BINAM derivatives was observed. MDPI 2020-06-06 /pmc/articles/PMC7308982/ /pubmed/32517228 http://dx.doi.org/10.3390/s20113234 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Shaferov, Alexander V.
Malysheva, Anna S.
Averin, Alexei D.
Maloshitskaya, Olga A.
Beletskaya, Irina P.
Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors
title Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors
title_full Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors
title_fullStr Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors
title_full_unstemmed Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors
title_short Synthesis and Evaluation of the (S)-BINAM Derivatives as Fluorescent Enantioselective Detectors
title_sort synthesis and evaluation of the (s)-binam derivatives as fluorescent enantioselective detectors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308982/
https://www.ncbi.nlm.nih.gov/pubmed/32517228
http://dx.doi.org/10.3390/s20113234
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