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Pharmacological Approach to Smoking Cessation: An Updated Review for Daily Clinical Practice
Tobacco use is one of the major public health concerns and it is the most preventable cause of morbidity and mortality worldwide. Smoking cessation reduces subsequent cardiovascular events and mortality. Smoking is a real chronic disorder characterized by the development of an addiction status mainl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309212/ https://www.ncbi.nlm.nih.gov/pubmed/32578165 http://dx.doi.org/10.1007/s40292-020-00396-9 |
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author | Giulietti, Federico Filipponi, Andrea Rosettani, Giulia Giordano, Piero Iacoacci, Corrado Spannella, Francesco Sarzani, Riccardo |
author_facet | Giulietti, Federico Filipponi, Andrea Rosettani, Giulia Giordano, Piero Iacoacci, Corrado Spannella, Francesco Sarzani, Riccardo |
author_sort | Giulietti, Federico |
collection | PubMed |
description | Tobacco use is one of the major public health concerns and it is the most preventable cause of morbidity and mortality worldwide. Smoking cessation reduces subsequent cardiovascular events and mortality. Smoking is a real chronic disorder characterized by the development of an addiction status mainly due to nicotine. This condition makes the smokers generally unable to quit smoking without help. Different strategies are available to treat smoking dependence that include both non-pharmacological (behavioral counselling) and pharmacological therapies. Currently, it is well accepted that smoking cessation drugs are effective and safe in real-world settings. Nicotine replacement therapy (NRT), varenicline, bupropion and cytisine are the main pharmacological strategies available for smoking cessation. Their efficacy and safety have been proved even in patients with chronic cardiovascular disease. Each of these drugs has peculiar characteristics and the clinician should customize the smoking cessation strategy based on currently available scientific evidence and patient's preference, paying particular attention to those patients having specific cardiovascular and psychiatric comorbidities. The present document aims to summarize the current viable pharmacological strategies for smoking cessation, also discussing the controversial issue regarding the use of alternative tobacco products, in order to provide useful practical indications to all physicians, mainly to those involved in cardiovascular prevention. |
format | Online Article Text |
id | pubmed-7309212 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-73092122020-06-23 Pharmacological Approach to Smoking Cessation: An Updated Review for Daily Clinical Practice Giulietti, Federico Filipponi, Andrea Rosettani, Giulia Giordano, Piero Iacoacci, Corrado Spannella, Francesco Sarzani, Riccardo High Blood Press Cardiovasc Prev Review Article Tobacco use is one of the major public health concerns and it is the most preventable cause of morbidity and mortality worldwide. Smoking cessation reduces subsequent cardiovascular events and mortality. Smoking is a real chronic disorder characterized by the development of an addiction status mainly due to nicotine. This condition makes the smokers generally unable to quit smoking without help. Different strategies are available to treat smoking dependence that include both non-pharmacological (behavioral counselling) and pharmacological therapies. Currently, it is well accepted that smoking cessation drugs are effective and safe in real-world settings. Nicotine replacement therapy (NRT), varenicline, bupropion and cytisine are the main pharmacological strategies available for smoking cessation. Their efficacy and safety have been proved even in patients with chronic cardiovascular disease. Each of these drugs has peculiar characteristics and the clinician should customize the smoking cessation strategy based on currently available scientific evidence and patient's preference, paying particular attention to those patients having specific cardiovascular and psychiatric comorbidities. The present document aims to summarize the current viable pharmacological strategies for smoking cessation, also discussing the controversial issue regarding the use of alternative tobacco products, in order to provide useful practical indications to all physicians, mainly to those involved in cardiovascular prevention. Springer International Publishing 2020-06-23 2020 /pmc/articles/PMC7309212/ /pubmed/32578165 http://dx.doi.org/10.1007/s40292-020-00396-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Review Article Giulietti, Federico Filipponi, Andrea Rosettani, Giulia Giordano, Piero Iacoacci, Corrado Spannella, Francesco Sarzani, Riccardo Pharmacological Approach to Smoking Cessation: An Updated Review for Daily Clinical Practice |
title | Pharmacological Approach to Smoking Cessation: An Updated Review for Daily Clinical Practice |
title_full | Pharmacological Approach to Smoking Cessation: An Updated Review for Daily Clinical Practice |
title_fullStr | Pharmacological Approach to Smoking Cessation: An Updated Review for Daily Clinical Practice |
title_full_unstemmed | Pharmacological Approach to Smoking Cessation: An Updated Review for Daily Clinical Practice |
title_short | Pharmacological Approach to Smoking Cessation: An Updated Review for Daily Clinical Practice |
title_sort | pharmacological approach to smoking cessation: an updated review for daily clinical practice |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309212/ https://www.ncbi.nlm.nih.gov/pubmed/32578165 http://dx.doi.org/10.1007/s40292-020-00396-9 |
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